118427-36-4

Basic information

• Product Name: 4-Pentenoic acid, 4-chloro-2,2-dimethyl- ethyl ester
• Synonyms: 4-Pentenoic acid, 4-chloro-2,2-dimethyl- ethyl ester;ethyl 4-chloro-2,2-dimethylpent-4-enoate
• CAS NO: 118427-36-4
• Molecular Formula: C9H15ClO2
• Molecular Weight: 190.67
• Product Categories: Miscellaneous Reagents
• Mol File: 118427-36-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 60-65°C
• Flash Point: 81.8°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 0.194mmHg at 25°C
• Refractive Index: 1.446
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Pentenoic acid, 4-chloro-2,2-dimethyl- ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 4-chloro-2,2-dimethyl- ethyl ester(118427-36-4)
• EPA Substance Registry System: 4-Pentenoic acid, 4-chloro-2,2-dimethyl- ethyl ester(118427-36-4)

Safety Data

• Hazardous Substances Data: 118427-36-4(Hazardous Substances Data)

Usage

Description

4-Pentenoic acid, 4-chloro-2,2-dimethylethyl ester, also known as 4-Chloro-2,2-dimethyl-4-pentenoic Acid Ethyl Ester (CAS# 118427-36-4), is an organic compound that is characterized as a colorless oil. It is primarily used in the field of organic synthesis due to its unique chemical properties.

Uses

Used in Organic Synthesis:
4-Pentenoic acid, 4-chloro-2,2-dimethylethyl ester is used as a synthetic intermediate for the production of various chemicals and pharmaceuticals. Its chemical structure allows it to be a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Pentenoic acid, 4-chloro-2,2-dimethylethyl ester is used as a key component in the development of new drugs. Its unique properties make it a valuable asset in the creation of novel therapeutic agents.
Used in Chemical Research:
4-Pentenoic acid, 4-chloro-2,2-dimethylethyl ester is also utilized in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic pathways. Its colorless oil form makes it an ideal candidate for such investigations.

InChI:InChI=1/C9H15ClO2/c1-5-12-8(11)9(3,4)6-7(2)10/h2,5-6H2,1,3-4H3

Upstream product

• 78-88-6 2,3-Dichloroprop-1-ene 
• 97-62-1 Ethyl isobutyrate 

Downstream Products

• 154325-75-4 5-bromo-2,2-dimethyl-4-oxopentanoic acid ethyl ester 
• 136558-13-9 ethyl 5-t-butylthio-2,2-dimethyl-4-oxo-pentanoate 

Relevant articles and documents

COMPOUNDS AND METHODS FOR TREATMENT OF HEDGEHOG PATHWAY ASSOCIATED CONDITIONS

Provided herein is novel compounds of formula (I), (II), (III), (IV), and (V) as described in the specification, and pharmaceutically acceptable salts, solvates, and prodrugs and compositions thereof, and methods of measuring hedgehog pathway activation in tumor cells, examining tumor cell proliferation, differentiation and apoptosis and using the compounds and pharmaceutical compositions disclosed for treatment of diseases and disorders associated with the hedgehog signaling pathway.

Compound as well as preparation method and application thereof

The invention relates to a compound. The structural formula of the compound is shown as formula (1) in the description, wherein R is H or CH3. The invention further provides a preparation method of the compound and an application of the compound or pharmaceutically acceptable salt, solvate or drug complex of the compound to preparation of drugs for treating hedgehog pathway activation-related diseases. The compound can be used for preparing the drugs for treating the hedgehog pathway activation-related diseases, can well inhibit medulloblastoma growth and can be used for preparing drugs for treating medulloblastoma-related diseases.

New-type compound and preparation method and application thereof

The invention relates to a new-type compound. A structural formula of the new-type compound is as shown in a formula (1). The invention further provides a method for preparing the above new-type compound. The invention further provides an application of the above new-type compound or pharmaceutically acceptable salt thereof, a solvate or a drug compound for preparing a drug for treating a diseaserelated to activation of a hedgehog passage. The provided above new-type compound can be used for preparing the drug for treating the disease related to the activation of the hedgehog passage. The new-type compound is particularly capable of inhibiting growth of medulloblastoma well, and can be used for preparing a drug for treating medulloblastoma related diseases.