118427-38-6

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 5-chloro-3-(phenylthio)-
• CAS NO: 118427-38-6
• Molecular Formula: C15H10ClNO2S
• Molecular Weight: 303.769
• Mol File: 118427-38-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 5-chloro-3-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 5-chloro-3-(phenylthio)-(118427-38-6)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 5-chloro-3-(phenylthio)-(118427-38-6)

Safety Data

• Hazardous Substances Data: 118427-38-6(Hazardous Substances Data)

Upstream product

• 118427-37-5 ethyl 3-phenylthio-5-chloroindole-2-carboxylate 
• 10519-96-7 potassium trimethylsilonate 
• 10517-21-2 5-chloro-1H-Indole-2-carboxylic acid 
• 882-33-7 diphenyldisulfane 

Downstream Products

• 158561-89-8 5-chloro-3-(phenylsulfonyl)-1H-indole-2-carboxylic acid 
• 148473-24-9 methyl 3-(phenylthio)-5-chloro-1H-indole-2-carboxylate 
• 148473-16-9 5-chloro-3-(phenylthio)-1H-indole-2-carboxamide 
• 540740-62-3 methyl 5-chloro-3-phenylsulfonyl-1H-indole-2-carboxylate 
• 148472-83-7 5-chloro-3-(phenyl)sulfonyl-1H-indole-2-carboxamide 

Relevant articles and documents

Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: Synthesis and SAR studies

The potent anti-HIV-1 activities of L-737,126 (2) and PAS sulfones prompted us to design and test against HIV-1 in acutely infected MT-4 cells a number of novel 1- and 3-benzenesulfonylindoles. Indoles belonging to the 1-benzenesulfonyl series were found

5-Chloro-3-(phenylsulfonyl)indole-2-carboxamide: A novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase

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3-hetero-substituted-N-benzyl-indoles

Compounds having the formula: are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labour, spontaneous abortion, dysmenorrhea, and migraine.