118476-12-3

Basic information

• Product Name: Benzenamine, 2-(1-heptynyl)-
• CAS NO: 118476-12-3
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• Mol File: 118476-12-3.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(1-heptynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(1-heptynyl)-(118476-12-3)
• EPA Substance Registry System: Benzenamine, 2-(1-heptynyl)-(118476-12-3)

Safety Data

• Hazardous Substances Data: 118476-12-3(Hazardous Substances Data)

Upstream product

• 628-71-7 1-Heptyne 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 69561-06-4 1-(2-aminophenyl)-heptan-1-one 
• 121866-22-6 2-heptylphenylamine 
• 1162682-06-5 N-(2-(hept-1-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 1313483-58-7 N-ethynyl-N-(2-hept-1-ynyl-phenyl)-4-methyl-benzenesulfonamide 
• 1313483-59-8 1-pentyl-5-(toluene-4-sulfonyl)-5H-γ-carboline-3-carboxylic acid methyl ester 
• 1333391-82-4 4-(2-pentyl-1H-indol-3-yl)phenol 
• 1333391-83-5 2,6-dimethyl-4-(2-pentyl-1H-indol-3-yl)aniline 
• 1333391-98-2 1-azido-2-(hept-1-ynyl)benzene 
• 1333391-70-0 2-pentyl-2-(1-phenylallyl)indolin-3-one 
• 253435-16-4 2-(1-heptynyl)-1-iodobenzene 

Relevant articles and documents

Complex Annulations through Silver Carbenoid Intermediate: An Alternative Entry to Transformations of 1,2,3-Triazoles

An alternative entry to transformations of N-sulfonyl-4-(2-(ethynyl)aryl)-1,2,3-triazoles with various generated in situ or external nucleophiles by means of silver catalysis for producing diverse functionalized isoquinolines is described. Mechanistically

A Synthetic Route to Chiral Benzo-Fused N-Heterocycles via Sequential Intramolecular Hydroamination and Asymmetric Hydrogenation of Anilino-Alkynes

An efficient sequential intramolecular hydroamination/asymmetric hydrogenation reaction under catalysis of a single chiral ruthenium complex or a binary system consisting of achiral gold complex and chiral ruthenium complex has been reported. A diverse range of enantioenriched benzo-fused N-heterocycles, including 1,2,3,4-tetrahydroquinoline, indoline, and 2,3,4,5-tetrahydro-1H-benzo[b]azepine derivatives, were obtained from anilino-alkynes in high yields (up to 98%) with moderate to excellent enantioselectivities (up to 98% ee) under mild conditions. This protocol features good functional group tolerance and high atom economy. Furthermore, this catalytic protocol is applicable to gram-scale synthesis of a naturally occurring alkaloid, (-)-Angustureine.

Palladium-Catalyzed Construction of Tetracyclic Scaffolds via the 1,7-Enyne Carbocyclization/Iodophenol Dearomatization Cascade

An efficient palladium-catalyzed dearomatizing [2+2+1] carbocyclization of 1,7-enynes with iodophenols has been developed. A type of tetracyclic scaffold was built in this reaction, exhibiting a broad substrate scope with moderate to excellent yields. More importantly, this method provides a potential strategy for the synthesis of tetracyclic skeleton natural products.