1185240-22-5
Post Buying Request-
-
Basic information
- Product Name: A77 1726-D4
- Synonyms: A77 1726-D4;N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide-d4, LEF-M-d4;TeriflunoMide-d4;TeriflunoMide-D4/ FlucyaMide-D4 / A77 1726-D4;Leflunomide-d4 Metabolite (Teriflunomide-d4)
- CAS NO:1185240-22-5
- Molecular Formula: C12H9F3N2O2
- Molecular Weight: 270.2072696
- EINECS: N/A
- Product Categories: Isotope Labeled Compounds;Metabolites & Impurities;Tyrosine Kinase Inhibitors;Isotope Labelled Compounds
- Mol File: 1185240-22-5.mol
- Article Data: 0
-
Chemical Properties
- Melting Point: 214-217°C
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer
- Solubility: N/A
- CAS DataBase Reference: A77 1726-D4(CAS DataBase Reference)
- NIST Chemistry Reference: A77 1726-D4(1185240-22-5)
- EPA Substance Registry System: A77 1726-D4(1185240-22-5)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- RIDADR: UN 1648 3 / PGII
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1185240-22-5(Hazardous Substances Data)
1185240-22-5 Suppliers
Recommended suppliersmore
1185240-22-5 Usage
Description
A77 1726-D4, also known as Teriflunomide-d4, is a stable-labeled internal standard of Teriflunomide, which is the active metabolite of Leflunomide, an immunosuppressive disease-modifying antirheumatic drug. It is an off-white solid and is suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays.Uses
Used in Pharmaceutical Industry:A77 1726-D4 is used as an internal standard for the quantification of Leflunomide metabolite by GCor LC-mass spectrometry. It helps in the accurate measurement and monitoring of Leflunomide levels in patients, ensuring effective treatment and minimizing side effects.
Used in Rheumatology:
A77 1726-D4 is used in the treatment of rheumatoid arthritis as the active metabolite of Leflunomide. It interferes with dendritic cell function, which plays a crucial role in the immune response, thereby helping to manage the symptoms and progression of rheumatoid arthritis.
Used in Clinical and Diagnostic Testing:
A77 1726-D4 is used as a stable-labeled internal standard in clinical and diagnostic testing, such as therapeutic drug monitoring assays. It ensures the accuracy and reliability of test results, aiding in the diagnosis and treatment of various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1185240-22-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,2,4 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1185240-22:
(9*1)+(8*1)+(7*8)+(6*5)+(5*2)+(4*4)+(3*0)+(2*2)+(1*2)=135
135 % 10 = 5
So 1185240-22-5 is a valid CAS Registry Number.
1185240-22-5Upstream product
1185240-22-5Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1185240-22-5
A77 1726-D4
