1185296-18-7

Basic information

• Product Name: C₄₅H₅₁NO₅
• Synonyms: C₄₅H₅₁NO₅
• CAS NO: 1185296-18-7
• Molecular Weight: 685.904
• Mol File: 1185296-18-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₅H₅₁NO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₅H₅₁NO₅(1185296-18-7)
• EPA Substance Registry System: C₄₅H₅₁NO₅(1185296-18-7)

Safety Data

• Hazardous Substances Data: 1185296-18-7(Hazardous Substances Data)

Upstream product

• 566-66-5 3β-hydroxy-pregn-4-en-20-one 
• 35661-40-6 N-Fmoc L-Phe 

Downstream Products

• 1185295-59-3 C₃₀H₄₁NO₃ 

Relevant articles and documents

Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury

Preclinical and clinical research findings have revealed that the hormone progesterone, when acutely administered, can dramatically reduce cerebral edema, inflammation, tissue necrosis, and programmed cell death following traumatic brain injury (TBI). The poor aqueous solubility of progesterone, however, limits its potential use as a therapeutic. Several chemically novel analogues of progesterone and its natural metabolite allopregnanolone have been synthesized and screened using both in vitro and whole animal models of TBI. The new derivatives demonstrated greatly improved solubility and select compounds have shown equivalent effectiveness to progesterone in reducing cerebral edema after TBI. 2009 American Chemical Society.