1186-52-3 Usage
Description
ACETIC-D3 ACID-D, also known as deuterated acetic acid, is a colorless liquid used in various applications due to its unique chemical properties. It is a deuterated NMR solvent containing 0.03% (v/v) TMS (tetramethylsilane) and is particularly useful in NMR-based research and analyses. The dissociation constant of ACETIC-D3 ACID-D in deuterium oxide has been obtained over a range of temperatures using the emf method.
Uses
1. Used in NMR Spectroscopy:
ACETIC-D3 ACID-D is used as an NMR solvent for the analysis and profiling of biological samples resolved through NMR spectroscopy. It is particularly useful for labeling RNA for high-resolution NMR.
2. Used in Food Industry:
ACETIC-D3 ACID-D serves as a deuterated, polar, and protic solvent in the food industry. It is used as a preservative, pH control agent, and flavor enhancer, contributing to the quality and shelf life of various food products.
3. Used in Chemical Synthesis:
ACETIC-D3 ACID-D may be used in the synthesis of deuterated compounds, such as (7E,9Z)-CLA (conjugated linoleic acid) and Pr(CD3COO)3.D2O (deuterium analog of praseodymium (III) acetate hydrate). These synthesized compounds have potential applications in various fields, including pharmaceuticals and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1186-52-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1186-52:
(6*1)+(5*1)+(4*8)+(3*6)+(2*5)+(1*2)=73
73 % 10 = 3
So 1186-52-3 is a valid CAS Registry Number.
InChI:InChI=1/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/i1D3/hD
1186-52-3Relevant articles and documents
Potter,Ritter
, p. 1040 (1954)
1,1-Ethenediol: The Long Elusive Enol of Acetic Acid
Eckhardt, André K.,Mardyukov, Artur,Schreiner, Peter R.
, (2020)
We present the first spectroscopic identification of hitherto unknown 1,1-ethenediol, the enol tautomer of acetic acid. The title compound was generated in the gas phase through flash vacuum pyrolysis of malonic acid at 400 °C. The pyrolysis products were
Ortho-Deuteration of Aromatic Aldehydes via a Transient Directing Group-Enabled Pd-Catalyzed Hydrogen Isotope Exchange
Kong, Junhua,Jiang, Zhi-Jiang,Xu, Jiayuan,Li, Yan,Cao, Hong,Ding, Yanan,Tang, Bencan,Chen, Jia,Gao, Zhanghua
, p. 13350 - 13359 (2021/10/01)
A practical and scalable ortho-selective deuteration of aromatic aldehydes was accomplished by Pd-catalyzed hydrogen isotope exchange with deuterium oxide as an inexpensive deuterium source. The use of tert-leucine as a transient directing group facilitates the exchange, affording a wide range of ortho-deuterated aromatic aldehydes with deuterium incorporation up to 97%. The control experiments suggest that the addition of silver trifluoroacetate resists the unexpected reduction of Pd(II), while the theoretical study indicates a rapid reversible concerted metalation-deprotonation process.
