1186238-74-3Relevant articles and documents
Palladium-catalyzed synthesis of free-NH indole 2-acetamides and derivatives from ethyl 3-(o-trifluoroacetamidoaryl)-1-propargylic carbonates
Cacchi, Sandro,Fabrizi, Giancarlo,Filisti, Eleonora
experimental part, p. 1817 - 1821 (2009/12/03)
The reaction of ethyl 3-(o-trifluoroacetamidoaryl)-1-propargylic carbonates with primary or secondary amines in the presence of Pd2(dba) 3, dppf, and carbon monoxide in THF at 80 °C provides ready access to free-NH indole 2-acetamide