1186415-53-1Relevant articles and documents
Dipeptidyl nitrile inhibitors of Cathepsin L
Asaad, Nabil,Bethel, Paul A.,Coulson, Michelle D.,Dawson, Jack E.,Ford, Susannah J.,Gerhardt, Stefan,Grist, Matthew,Hamlin, Gordon A.,James, Michael J.,Jones, Emma V.,Karoutchi, Galith I.,Kenny, Peter W.,Morley, Andrew D.,Oldham, Keith,Rankine, Neil,Ryan, David,Wells, Stuart L.,Wood, Linda,Augustin, Martin,Krapp, Stephan,Simader, Hannes,Steinbacher, Stefan
scheme or table, p. 4280 - 4283 (2010/04/30)
A series of potent Cathepsin L inhibitors with good selectivity with respect to other cysteine Cathepsins is described and SAR is discussed with reference to the crystal structure of a protein-ligand complex.
