118643-68-8

Basic information

• Product Name: (4-Nitro-benzyl)-phenyl-phosphinic acid (4S,5R)-5-iodomethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester
• CAS NO: 118643-68-8
• Molecular Weight: 531.284
• Mol File: 118643-68-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Nitro-benzyl)-phenyl-phosphinic acid (4S,5R)-5-iodomethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Nitro-benzyl)-phenyl-phosphinic acid (4S,5R)-5-iodomethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(118643-68-8)
• EPA Substance Registry System: (4-Nitro-benzyl)-phenyl-phosphinic acid (4S,5R)-5-iodomethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester(118643-68-8)

Safety Data

• Hazardous Substances Data: 118643-68-8(Hazardous Substances Data)

Upstream product

• 3145-86-6 4-nitrobenzyl iodide 
• 118643-74-6 (1S,7S)-9,9-dimethyl-4-phenyl-3,5,8,10,4-tetraoxaphosphabicyclo<5.3.0>decane 

Relevant articles and documents

Asymmetric Synthesis of Phosphine Oxides with the Arbuzov Reaction

The Arbuzov reaction of (5S,6S)-dimethoxy-2-phenyl-1,3,2-dioxaphosphacycloheptane with various alkyl halides produced acyclic phosphinates in a moderate to high diastereomer excess.The same reaction of (1S,7S)-9,9-dimethyl-4-phenyl-3,5,8,10,4-tetraoxaphosphabicyclodecane with the alkyl halides needed the more vigorous reaction conditions and gave phosphinates in a low diastereomer excess.These phosphinates were converted into optically active phosphine oxides.