118671-20-8

Basic information

• Product Name: N-(2-Cyanomethyl-phenyl)-benzamide
• Synonyms: N-(2-Cyanomethyl-phenyl)-benzamide
• CAS NO: 118671-20-8
• Molecular Weight: 236.273
• Mol File: 118671-20-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-Cyanomethyl-phenyl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Cyanomethyl-phenyl)-benzamide(118671-20-8)
• EPA Substance Registry System: N-(2-Cyanomethyl-phenyl)-benzamide(118671-20-8)

Safety Data

• Hazardous Substances Data: 118671-20-8(Hazardous Substances Data)

Upstream product

• 2973-50-4 2-aminophenylacetonitrile 
• 98-88-4 benzoyl chloride 

Downstream Products

• 51072-85-6 2-phenyl-1H-indole-3-carbonitrile 

Relevant articles and documents

Synihesis of 3-substituied indoles via a modified madeling reaction

Anilides 4a-c,e-k, lla-d in which the amide function is benzylated, or silylated and having different electron-withdrawing groups (EWG) at the methyl methyl in the ortho position of the amide function, cyclize under the influence of potassium tert-butoxide to the corresponding indole derivatives 5a-c,e-k and 9a-d, respectively, under these conditions the chloroacetamides 4d,n and 11e are converted into the tetrahydroquinolines 6a,b and 12, respectively. Treatment of chloroacetamide 4m with KOt-Bu gave, in addition to starting material, indole 5m, tetrahydroquinoline 6c and 2(1H)-quinolinone 7. When 3-indolecarbonitrile 5a is treated with sodium in liquid amnonia debenzylation takes place, while after catalytic hydrogenation with 5% Pd/C the corresponding 2,3-dirnethylindole 8 is formed.