1187449-10-0

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl-;4-bromo-5-chloro-2-cyclopropyl-1H-Pyrrolo[2,3-b]pyridine
• CAS NO: 1187449-10-0
• Molecular Formula: C₁₀H₈BrClN₂
• Molecular Weight: 271.54092
• Mol File: 1187449-10-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.795±0.06 g/cm3(Predicted)
• PKA: 12.69±0.40(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl-(1187449-10-0)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl-(1187449-10-0)

Safety Data

• Hazardous Substances Data: 1187449-10-0(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl- is a chemical compound with the molecular formula C9H6BrClN2. It is a heterocyclic compound that contains both a pyrrolopyridine and cyclopropyl group. This chemical is used in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds. Additionally, 1H-Pyrrolo[2,3-b]pyridine, 4-broMo-5-chloro-2-cyclopropyl- has potential applications in the field of medicinal chemistry and drug discovery due to its unique structural features. However, it is important to handle this compound with caution as it may have hazardous properties.

Upstream product

• 1187449-04-2 4-bromo-5-chloro-3-iodopyridin-2-amine 
• 1187449-01-9 2-amino-4-bromo-5-chloropyridine 
• 6746-94-7 Cyclopropylacetylene 
• 84249-14-9 2-amino-4-bromopyridine 
• 1187449-08-6 4-bromo-5-chloro-3-(cyclopropylethynyl)-2-pyridinamine 

Downstream Products

• 1187448-54-9 4-(5-chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(1,1-dioxotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 

Relevant articles and documents

NOVEL COMPOUNDS

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.