118762-10-0

Basic information

• Product Name: N-chloro-N,α-dimethylbenzylamine
• Synonyms: N-chloro-N,α-dimethylbenzylamine
• CAS NO: 118762-10-0
• Molecular Weight: 169.654
• Mol File: 118762-10-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-chloro-N,α-dimethylbenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-chloro-N,α-dimethylbenzylamine(118762-10-0)
• EPA Substance Registry System: N-chloro-N,α-dimethylbenzylamine(118762-10-0)

Safety Data

• Hazardous Substances Data: 118762-10-0(Hazardous Substances Data)

Upstream product

• 42882-26-8 N-methyl-N-(1-phenylethyl)amine 

Downstream Products

• 10557-01-4 (E)-N-(α-methylbenzylidene)methylamine 
• 5933-40-4 (R)-(+)-N,α-dimethylbenzylamine 
• 19131-99-8 N-methyl-N-[(S)-1-phenylethyl]amine 
• 6907-71-7 N-(1-phenylethylidene)methanamine 

Relevant articles and documents

A general and atom-efficient continuous-flow approach to prepare amines, amides and imines via reactive N-chloramines

Chloramines are an important class of reagents, providing a convenient source of chlorine or electrophilic nitrogen. However, the instability of these compounds is a problem which makes their isolation and handling difficult. To overcome these hazards, a continuous-flow approach is reported which generates and immediately reacts N-chloramines directly, avoiding purification and isolation steps. 2-Chloramines were produced from the reaction of styrenes with N-alkyl-N-sulfonyl-N-chloramines, whilst N-alkyl or N,N’-dialkyl-N-chloramines reacted with anisaldehyde in the presence of t-BuO2H oxidant to afford amides. Primary and secondary imines were produced under continuous conditions from the reaction of N-chloramines with base, with one example subsequently reduced under asymmetric conditions to produce a chiral amine in 94% ee.