1187740-53-9

Basic information

• Product Name: (3aR,8aS)-tetrahydro-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2,8(3H,4H)-dione
• Synonyms: (3aR,8aS)-tetrahydro-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2,8(3H,4H)-dione
• CAS NO: 1187740-53-9
• Molecular Weight: 366.484
• Mol File: 1187740-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aR,8aS)-tetrahydro-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2,8(3H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,8aS)-tetrahydro-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2,8(3H,4H)-dione(1187740-53-9)
• EPA Substance Registry System: (3aR,8aS)-tetrahydro-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2,8(3H,4H)-dione(1187740-53-9)

Safety Data

• Hazardous Substances Data: 1187740-53-9(Hazardous Substances Data)

Upstream product

• 593-60-2 Vinyl bromide 
• 28092-52-6 (3aS,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2,4-dione 

Downstream Products

• 1187740-55-1 (3aR,8S,8aS)-hexahydro-8-hydroxy-1,3-bis(phenylmethyl)-1H-thiepino-[3,4-d]imidazole-2(3H)-one 

Relevant articles and documents

Unexpected ring expansion of the (3aS,6aR)-γ-thiolactone moiety during the introduction of the (+)-biotin side chain

The reaction of vinylmagnesium bromide with the (3aS,6aR)-γ- thiolactone 2 in THF afforded, after unexpected ring expansion of the g-thiolactone moiety, the seven-membered-ring ketone 5 in excellent yield, instead of the expected tertiary alcohol 3.