1187831-58-8

Basic information

• Product Name: C₃₃H₃₁ClFN₅O₄S
• CAS NO: 1187831-58-8
• Molecular Weight: 648.158
• Mol File: 1187831-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₃H₃₁ClFN₅O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₃H₃₁ClFN₅O₄S(1187831-58-8)
• EPA Substance Registry System: C₃₃H₃₁ClFN₅O₄S(1187831-58-8)

Safety Data

• Hazardous Substances Data: 1187831-58-8(Hazardous Substances Data)

Upstream product

• 474022-76-9 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid hydrazide 
• 86393-33-1 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid 
• 1187831-48-6 C₃₁H₂₉ClFN₅O₃ 
• 68-11-1 mercaptoacetic acid 
• 1187831-38-4 C₂₀H₁₄Cl₂FN₃O₂ 
• 929904-81-4 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chloride 

Relevant articles and documents

Synthesis and antimicrobial study of fluoroquinolonebased 4-thiazolidinones

The title compounds 2-substituted phenyl-3-{1-cyclopropyl-6-fluoro- 7-[4-(4-methoxyphenylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline} carboxamido-1, 3-thiazolidin-4-ones 6a-j have been synthesized from lead molecule 7-chloro-1- cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1; this reacted with thionyl chloride to give acid chloride 2 and with hydrazine hydrate to afford hydrazide 3. The hydrazide 3 on condensation with substituted aromatic aldehydes a-j gave Schiff base; these on reaction with N-(4-methoxyphenyl) piperazine and thioglycolic acid furnished title compounds 6a-j. All of the synthesized compounds have been established by elemental analysis. IR and NMR spectral data and have been screened for antifungal and antibacterial activities. Birkhaeuser Boston 2009.