118818-40-9

Basic information

• Product Name: 2-(N-amino-4-methoxyanilino)tropone
• CAS NO: 118818-40-9
• Molecular Weight: 242.277
• Mol File: 118818-40-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(N-amino-4-methoxyanilino)tropone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-amino-4-methoxyanilino)tropone(118818-40-9)
• EPA Substance Registry System: 2-(N-amino-4-methoxyanilino)tropone(118818-40-9)

Safety Data

• Hazardous Substances Data: 118818-40-9(Hazardous Substances Data)

Upstream product

• 533-75-5 2-hydroxy-2,4,6-cycloheptatrien-1-one 
• 38768-08-0 2-(tosyloxy)tropone 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 

Downstream Products

• 118818-41-0 N-(4-methoxyphenyl)-2-aminotropone 

Relevant articles and documents

Synthesis and Reactions of 2-Arylhydrazinotropones. I. Preparation of 2-(2-Arylhydrazino)tropones and the 4-Substituted Derivatives

A wide variety of 2-(2-arylhydrazino)tropones were prepared by the reactions of 2-tosyloxytropone with arylhydrazines.The dimeric compounds 6,6'-bis(arylhydrazono)-1,1'-bi(2,4-cycloheptadiene)-7,7'-diones, 2-anilinotropones, and 3-(2-arylhydrazino)tropones were isolated as minor products in some cases.Similarly, starting with 2-tosyloxytropones bearing an isopropyl, isopropenyl, (1-acetamidoethyl), and protected acetyl group at the 5-position, 4-substituted 2-(2-arylhydrazino)tropones were obtained as the major products by the abnormal substitution reaction.These 2-(2-arylhydrazino)tropones are expected to effectively serve as precursor for a convenient synthesis of 5-aryl-substituted tropolones via benzidine-type rearrangement. 1H NMR (200 or 500-MHz) parameters for these 4-substituted 2-(2-arylhydrazino)tropones are given for their unambiguous structural assignments.