1188331-23-8 Usage
Description
3-AMINO-2-OXAZOLIDINONE D4 is a white solid compound that serves as a valuable tool in analytical chemistry and pharmaceutical research. It is a deuterated analogue of 3-amino-2-oxazolidinone, which allows for enhanced detection and quantification in mass spectrometry-based techniques.
Uses
Used in Pharmaceutical Research:
3-AMINO-2-OXAZOLIDINONE D4 is used as an internal standard for the quantification of AOZ (3-amino-2-oxazolidinone) by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry. Its deuterated nature provides a distinct mass signature, enabling accurate measurement and comparison of AOZ levels in various samples.
Used in Metabolite Analysis:
3-AMINO-2-OXAZOLIDINONE D4 also serves as a labelled metabolite of Furazolidone, a nitrofuran antibiotic. This application is particularly useful in studying the metabolic pathways and pharmacokinetics of Furazolidone, as well as in detecting and monitoring its presence in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1188331-23-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,8,3,3 and 1 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1188331-23:
(9*1)+(8*1)+(7*8)+(6*8)+(5*3)+(4*3)+(3*1)+(2*2)+(1*3)=158
158 % 10 = 8
So 1188331-23-8 is a valid CAS Registry Number.
1188331-23-8Relevant articles and documents
Stable-isotope-labeled furazolidone metabolite and synthesis method thereof
-
Paragraph 0023; 0028; 0030; 0033; 0034; 0037, (2020/05/02)
The invention discloses a stable-isotope-labeled furazolidone metabolite and a synthesis method thereof. The synthesis method comprises the following steps: S1, reacting stable-isotope-labeled 2-bromoethanol with hydrazine hydrate to synthesize stable-isotope-labeled 2-hydrazinoethanol; and S2, reacting the stable-isotope-labeled 2-hydrazinoethanol with dimethyl carbonate to synthesize the stable-isotope-labeled furazolidone metabolite. The invention provides the synthetic method of the stable-isotope-labeled furazolidone metabolite for the first time; the stable isotope labeling raw materialis cheap and easy to obtain, the synthesis process is simple, the product is easy to separate and purify, and the chemical purity and isotope abundance of the obtained product both reach 99% or above,meeting the requirement for serving as a standard reagent for quantitatively detecting furazolidone metabolite. The metabolite is high in use value and good in economy performance.
