1189428-23-6

Basic information

• Product Name: Valdecoxib-13C2, 15N
• Synonyms: Valdecoxib-13C2, 15N;4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonaMide-13C2,15N;Bextra-13C2,15N;SC 65872-13C2,15N;Valecoxib-13C2,15N;Valus-13C2,15N
• CAS NO: 1189428-23-6
• Molecular Formula: C16H14N2O3S
• Molecular Weight: 314.35896
• Product Categories: Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Amines;Aromatics;Heterocycles;Isotope Labelled Compounds;Sulfur & Selenium Compounds
• Mol File: 1189428-23-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 161-1630C
• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly)
• CAS DataBase Reference: Valdecoxib-13C2, 15N(CAS DataBase Reference)
• NIST Chemistry Reference: Valdecoxib-13C2, 15N(1189428-23-6)
• EPA Substance Registry System: Valdecoxib-13C2, 15N(1189428-23-6)

Safety Data

• Hazardous Substances Data: 1189428-23-6(Hazardous Substances Data)

Usage

Description

Valdecoxib-13C2, 15N is a labeled version of Valdecoxib, a nonsteroidal anti-inflammatory drug (NSAID) that is known for its anti-inflammatory, analgesic, and antipyretic properties in animal models. It functions as an inhibitor of prostaglandin synthesis, primarily through the inhibition of COX-2. The compound is characterized by its white solid appearance.

Uses

Used in Pharmaceutical Industry:
Valdecoxib-13C2, 15N is used as a labeled compound for research and development purposes in the pharmaceutical industry. It aids in the study of the pharmacokinetics, metabolism, and mechanism of action of Valdecoxib, which can lead to the development of more effective and safer NSAIDs.
Used in Preclinical Research:
Valdecoxib-13C2, 15N is used as a labeled NSAID for preclinical research, particularly in animal models. It helps researchers understand the drug's efficacy, safety, and potential side effects before it is tested in clinical trials.
Used in Drug Interaction Studies:
Valdecoxib-13C2, 15N is used as a labeled compound in drug interaction studies. It can help identify potential drug-drug interactions and assess the impact of other medications on the pharmacokinetics and pharmacodynamics of Valdecoxib.
Used in Analytical Chemistry:
Valdecoxib-13C2, 15N is used as a labeled standard in analytical chemistry for the development and validation of analytical methods, such as liquid chromatography-mass spectrometry (LC-MS) or gas chromatography-mass spectrometry (GC-MS), for the quantification and identification of Valdecoxib in biological samples.
Used in Toxicology Studies:
Valdecoxib-13C2, 15N is used as a labeled compound in toxicology studies to investigate the toxic effects of Valdecoxib and its metabolites, as well as to assess the potential for drug-induced toxicity in various organs and tissues.