1189449-70-4

Basic information

• Product Name: Amodiaquine-d10
• Synonyms: NSC 13453-10;Phenol, 4-[(7-chloro-4-quinolinyl)aMino]-2-[(diethylaMino-d10)Methyl]-;Amodiaquine-d10;4-[(7-Chloro-4-quinolyl)aMino]-α-(diethylaMino-d10)-o-cresol;CaMochin-d10;CaMoquinal-d10;CaMoquin-d10;CaMoquine-d10
• CAS NO: 1189449-70-4
• Molecular Formula: C20H22ClN3O
• Molecular Weight: 355.86118
• Product Categories: Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1189449-70-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 194-198°C
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Amodiaquine-d10(CAS DataBase Reference)
• NIST Chemistry Reference: Amodiaquine-d10(1189449-70-4)
• EPA Substance Registry System: Amodiaquine-d10(1189449-70-4)

Safety Data

• Hazardous Substances Data: 1189449-70-4(Hazardous Substances Data)

Usage

Description

Amodiaquine-d10 is a deuterated analog of the antimalarial drug amodiaquine, designed to serve as an internal standard for the quantification of amodiaquine by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry (MS). It is a pale yellow solid and is used to ensure accurate and reliable measurements of amodiaquine levels in various applications.

Uses

Used in Pharmaceutical Industry:
Amodiaquine-d10 is used as an internal standard for the quantification of amodiaquine in the pharmaceutical industry. This application is crucial for ensuring the accurate measurement of amodiaquine levels in drug development, quality control, and therapeutic drug monitoring.
Used in Antimalarial Research:
Amodiaquine-d10 is used as a research tool in the study of antimalarial compounds. It helps researchers understand the pharmacokinetics, pharmacodynamics, and potential synergistic effects of amodiaquine when used in combination with other antimalarial drugs, such as N-desethyl amodiaquine.
Used in Malaria Treatment Monitoring:
Amodiaquine-d10 is used as a reference compound in the monitoring of malaria treatment efficacy. By using Amodiaquine-d10 as an internal standard, healthcare professionals can accurately measure the levels of amodiaquine in a patient's blood, ensuring that the drug is administered at the correct dosage and is effective against the malaria parasite.
Used in Quality Control and Standardization:
Amodiaquine-d10 is used in the quality control and standardization of antimalarial drug products. It helps ensure that the active pharmaceutical ingredient (API) in these products meets the required specifications and is consistent in terms of purity, potency, and stability.