118970-92-6 Usage
Description
(S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL, with the molecular formula C16H23NO, is a chiral alcohol featuring a pyrrolidine ring, a benzyl group, and a hydroxyl group attached to a propan-2-ol moiety. (S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL is widely utilized in the synthesis of pharmaceuticals and other organic compounds, and it has demonstrated potential as a chiral auxiliary in asymmetric synthesis. Moreover, it has been explored for its therapeutic potential in treating neurological and mood disorders.
Uses
Used in Pharmaceutical Synthesis:
(S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL is used as a key intermediate in the synthesis of various drugs, contributing to the development of novel pharmaceuticals with improved efficacy and safety profiles.
Used in Asymmetric Synthesis:
In the field of organic chemistry, (S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL serves as a chiral auxiliary, playing a crucial role in asymmetric synthesis to produce enantiomerically pure compounds, which are essential for the pharmaceutical industry.
Used in the Treatment of Neurological Disorders:
(S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL is being investigated for its potential therapeutic applications in the treatment of neurological disorders, given its unique structural features and biological activities.
Used in the Treatment of Mood Disorders:
(S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL is also being explored for its potential use in the treatment of mood disorders, as it may offer new avenues for developing more effective therapies for patients suffering from such conditions.
Used in Chemical Research:
(S)-2-(1-BENZYLPYRROLIDIN-2-YL)PROPAN-2-OL is utilized in chemical research to study the effects of chirality on the properties and reactivity of molecules, which can lead to advancements in the design and synthesis of new compounds with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 118970-92-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,9,7 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 118970-92:
(8*1)+(7*1)+(6*8)+(5*9)+(4*7)+(3*0)+(2*9)+(1*2)=156
156 % 10 = 6
So 118970-92-6 is a valid CAS Registry Number.
118970-92-6Relevant articles and documents
Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Modulation of Enantiomeric Excess
Br?uer, Thomas M.,Zhang, Qi,Tiefenbacher, Konrad
, p. 7698 - 7701 (2016/07/07)
The noncovalent combination of a supramolecular host with iminium organocatalysis is described. Due to cation–π interactions the reactive iminium species is held inside the host and reacts in this confined environment. The products formed differ up to 92 % ee from the control experiments without added host. A model rationalizing the observed difference is presented.
PYRAZINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS
-
Page/Page column 91-92, (2010/06/15)
Pyrazine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Water-compatible iminium activation: Organocatalytic Michael reactions of carbon-centered nucleophiles with enals
Palomo, Claudio,Landa, Aitor,Mielgo, Antonia,Oiarbide, Mikel,Puente, Angel,Vera, Silvia
, p. 8431 - 8435 (2008/09/19)
(Chemical Equation Presented) A pool of water-compatible catalysts, namely the chiral prolinol-based catalysts 1, has been developed for highly enantioselective C-C bond-forming Michael reactions in water (see scheme). The synthesis of (S)-Rolipram, a type IV phosphodiesterase inhibitor, was also demonstrated.
