119022-15-0Relevant articles and documents
Solvent-free microwave synthesis of 4-hydroxy-3-phenylquinolin-2(1H)-ones and variants using activated arylmalonates
Rivkin, Alexey,Adams, Bruce
, p. 2395 - 2398 (2006)
The disclosure herein describes the rapid synthesis of 4-hydroxy-3-phenylquinolin-2(1H)-ones and variants via a solvent-free microwave cyclocondensation reaction using di-(2,4,6-trichlorophenyl)-2-phenylmalonate, which improves the general scope of this reaction.
Aktive Malonester als Synthons fuer Heterocyclen: Eine Methode zur Hertstellung von 4-Hydroxy-2(1H)-pyridonen
Kappe, Thomas,Ajili, Samir,Stadlbauer, Wolfgang
, p. 463 - 468 (2007/10/02)
4-Hydroxy-2-(1H)-pyridones 3 can be obtained in excellent yields from azomethines 1 with trichlorophenylmalonates 2.The variation of the substituents in position 1,3,5 or 6, respectively is possible over a wide range.In this manner the 5,6-fused-pyridones