119075-38-6

Basic information

• Product Name: 4-[2-(2-benzyl-phenoxy)-ethyl]-morpholine
• Synonyms: 4-[2-(2-benzyl-phenoxy)-ethyl]-morpholine
• CAS NO: 119075-38-6
• Molecular Weight: 297.397
• Mol File: 119075-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(2-benzyl-phenoxy)-ethyl]-morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(2-benzyl-phenoxy)-ethyl]-morpholine(119075-38-6)
• EPA Substance Registry System: 4-[2-(2-benzyl-phenoxy)-ethyl]-morpholine(119075-38-6)

Safety Data

• Hazardous Substances Data: 119075-38-6(Hazardous Substances Data)

Upstream product

• 3240-94-6 N-(2-chlorethyl)morpholine 
• 7563-58-8 Natrium-(2-benzyl-phenolat) 
• 28994-41-4 o-Benzylphenol 
• 110-91-8 morpholine 
• 165683-42-1 1-(2-bromoethoxy)-2-benzylbenzene 

Relevant articles and documents

Dopamine/serotonin receptor ligands. 9.1 oxygen-containing midsized heterocyclic ring systems and nonrigidized analogues. A step toward dopamine D5 receptor selectivity

Eleven-membered heterocycles (dibenz[g,j]-1-oxa-4-azacycloundecenes) and open-chain analogues were synthesized and investigated for affinities to human dopamine receptor subtypes. The moderately rigidized rings displayed nanomolar and subnanomolar Ki values at D1-like receptors with a significant D1 to D2 and a slight D5 to D 1 selectivity. The open-chain analogues showed lower affinities but significant D1 to D2 selectivities. Compound 3 (K i(D5) = 0.57 nmol) showed antagonistic or inverse agonistic binding characteristics in a functional Ca assay.