1191-43-1 Usage
Description
1,6-Hexanedithiol (HDT) is a long-chained bi-functional alkanethiol with 6 carbon atoms structured in a zig-zag pattern, forming a tetrahedral configuration. It is a clear colorless to slightly yellow liquid with a fatty, meaty odor. HDT forms a self-assembled monolayer (SAM) on a variety of substrates, effectively immobilizing the surface atoms.
Uses
Used in Electronics and Optoelectronics:
1,6-Hexanedithiol is used as a functionalizing agent for molybdenum disulphide (MoS2), which serves as a two-dimensional transition metal dichalcogenide (TMD) in electronics and optoelectronic devices. This application enhances the performance and functionality of these devices.
Used in Quantum Dots and Biosensors:
HDT forms a SAM on gallium arsenic (GaAs) doped cadmium sulfide (CdS) quantum dots (QDs), which can be utilized in biosensors and solar applications. This use capitalizes on the ability of HDT to immobilize surface atoms, improving the efficiency and stability of these applications.
Used in Self-Assembled Monolayers (SAMs):
1,6-Hexanedithiol is used in the formation of self-assembled monolayers (SAMs) on various substrates, providing a stable and organized surface for further applications in different industries.
Used in Synthetic Rubber:
1,6-Hexanedithiol is used as an additive in the synthetic rubber industry, where it contributes to the enhancement of the rubber's properties and performance.
Used in Food Industry:
1,6-Hexanedithiol is used in the food industry, particularly in the creation of food flavors and spices. It is also utilized in blending edible flavors for beef and poultry soup, adding depth and complexity to the taste.
Used in Flavoring Tobacco:
In the tobacco industry, HDT is employed as a flavoring agent, contributing to the overall taste and aroma of tobacco products.
Occurrence:
1,6-Hexanedithiol has been reported to be found in boiled beef, indicating its natural presence and potential use in the food industry as a flavor enhancer.
Chemical Properties:
1,6-Hexanedithiol has a fatty, meaty odor and is a clear colorless to slightly yellow liquid. According to FEMA, the total dithiol added to any food should not exceed 1.00 ppm, ensuring safety and quality in the food products.
Check Digit Verification of cas no
The CAS Registry Mumber 1191-43-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1191-43:
(6*1)+(5*1)+(4*9)+(3*1)+(2*4)+(1*3)=61
61 % 10 = 1
So 1191-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H14S2/c7-5-3-1-2-4-6-8/h7-8H,1-6H2
1191-43-1Relevant articles and documents
Catalytic Hydrogenation of Thioesters, Thiocarbamates, and Thioamides
Luo, Jie,Rauch, Michael,Avram, Liat,Ben-David, Yehoshoa,Milstein, David
supporting information, p. 21628 - 21633 (2021/01/11)
Direct hydrogenation of thioesters with H2 provides a facile and waste-free method to access alcohols and thiols. However, no report of this reaction is documented, possibly because of the incompatibility of the generated thiol with typical hydrogenation catalysts. Here, we report an efficient and selective hydrogenation of thioesters. The reaction is catalyzed by an acridine-based ruthenium complex without additives. Various thioesters were fully hydrogenated to the corresponding alcohols and thiols with excellent tolerance for amide, ester, and carboxylic acid groups. Thiocarbamates and thioamides also undergo hydrogenation under similar conditions, substantially extending the application of hydrogenation of organosulfur compounds.
Reduction of thiokols in the system hydrazine hydrate-base as a new route to alkanedithiols
Alekminskaya,Russavskaya,Korchevin,Deryagina,Trofimov
, p. 732 - 737 (2007/10/03)
A new procedure for preparative synthesis of alkanedithiols from simple commercially available products is based on reduction of the S-S bond in appropriate polyalkylene disulfides (thiokols) in the system hydrazine hydrate-base. Thiokols were prepared by reaction of dihaloalkanes with Na2S2 or K2S2 generated from elemental sulfur and alkali in aqueous hydrazine hydrate. Reaction of 1,2-dibromocyclohexane with sodium or potassium disulfide yields bis(2-bromocyclohexyl) sulfide as the only product.
A Reagent for Reduction of Disulfide Bonds in Proteins That Reduces Disulfide Bonds Faster Than Does Dithiothreitol
Singh, Rajeeva,Whitesides, George M.
, p. 2332 - 2337 (2007/10/02)
We have synthesized a new reagent - N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine (DMH) - for the reduction of disulfide bonds in proteins.DMH reduces disulfide bonds 7 times faster than does dithiothreitol (DTT) in water at pH 7.DMH reduces mixed disulfides of cysteine proteases (papain and ficin) especially rapidly (30 times faster than DTT).DMH (ε0 = -0.300 V) reduces noncyclic disulfides completely, although it is less strongly reducing than DTT (ε0 = -0.356 V).
