1191045-03-0

Basic information

• Product Name: 1-(2-fluoro-4-methoxy-phenylethynyl)-2,5-dimethoxy-3-methyl-benzene
• Synonyms: 1-(2-fluoro-4-methoxy-phenylethynyl)-2,5-dimethoxy-3-methyl-benzene
• CAS NO: 1191045-03-0
• Molecular Weight: 300.33
• Mol File: 1191045-03-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-fluoro-4-methoxy-phenylethynyl)-2,5-dimethoxy-3-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-fluoro-4-methoxy-phenylethynyl)-2,5-dimethoxy-3-methyl-benzene(1191045-03-0)
• EPA Substance Registry System: 1-(2-fluoro-4-methoxy-phenylethynyl)-2,5-dimethoxy-3-methyl-benzene(1191045-03-0)

Safety Data

• Hazardous Substances Data: 1191045-03-0(Hazardous Substances Data)

Upstream product

• 1191045-02-9 1-ethynyl-2,5-dimethoxy-3-methyl-benzene 
• 458-50-4 1-bromo-2-fluoro-4-methoxybenzene 
• 13523-12-1 1-bromo-2,5-dimethoxy-3-methylbenzene 
• 1191045-01-8 (2,5-dimethoxy-3-methyl-phenylethynyl)-trimethyl-silane 

Relevant articles and documents

NOVEL ESTROGEN RECEPTOR LIGANDS

The invention provides a pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt: wherein R3 is selected from the group consisting of ORA; -CHO; -C(O)C1-4alkyl; -C(O)phenyl; -O-C(O)RA; and N(RB)2; R6 is selected from certain cyclic groups defined in the specification; and the remaining groups are defined in the specification; together with a pharmaceutically acceptable carrier. Most of the compounds are novel. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity.