119169-63-0

Basic information

• Product Name: 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;Ethyl 4-chloro-1,3-diMethyl-1H-pyrazole-5-carboxylate
• CAS NO: 119169-63-0
• Molecular Formula: C8H11ClN2O2
• Molecular Weight: 202.63814
• Mol File: 119169-63-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(119169-63-0)
• EPA Substance Registry System: 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(119169-63-0)

Safety Data

• Hazardous Substances Data: 119169-63-0(Hazardous Substances Data)

Usage

General Description

4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER, also known as ethyl 4-chloro-1,3-dimethyl-1H-pyrazole-5-carboxylate, is a chemical compound with the molecular formula C9H12ClNO2. It is an ester derivative of 4-chloro-1,3-dimethyl-1H-pyrazole-5-carboxylic acid, and is commonly used in the synthesis of pharmaceutical compounds and agrochemicals. This chemical is a white to off-white crystalline solid that is sparingly soluble in water and has a melting point of approximately 75-80°C. It is often used as a building block or intermediate in organic synthesis processes, and is commonly found in research and development laboratories for the production of various compounds for pharmaceutical and agricultural applications.

Upstream product

• 5744-40-1 ethyl 1,3-dimethylpyrazole-5-carboxylate 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 

Downstream Products

• 98198-65-3 1,3-dimethyl-4-chloropyrazole-5-carboxylic acid 
• 128141-47-9 1,3-dimethyl-4-chloropyrazole-5-carboxylic acid chloride 

Relevant articles and documents

Synthesis and insecticidal activities of novel 1H-pyrazole-5-carboxylic acid derivatives

Fourteen 1H-pyrazole-5-carboxylic acid derivatives containing oxazole and thiazole rings were synthesized and characterized by 1H NMR, mass spectrometry and elemental analysis. Most target compounds were obtained in overall yields in the range of 30-50%. The insecticidal activities of these new compounds against Aphis fabae were evaluated. The bioassays' results indicate that some of these compounds exhibit good activities, especially compound 7h which shows 85.7% mortality against A. fabae at a concentration of 12.5 mg/L. This activity is comparable to that of the commercial insecticide imidacloprid.

ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C

A method of treating cancer comprises administering: (a) a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof; and (b) a therapeutically effective amount of an additional anti-cancer agent, to a subject in need of such treatment, the compound of Formula (I) being: where X, R1, R2, ring A, L1, L2, L3, and R5 are as defined in this disclosure.

A class of pyrazole derivatives, preparation method and application thereof (by machine translation)

The invention discloses a following formula stru - 1 indicated by the pyrazole derivatives, The definition of each substituent in the specification. This invention relates to pyrazole derivatives suitable for use in the pest. (by machine translation)