119197-25-0

Basic information

• Product Name: 3-CHLORO-4,4,4-TRIFLUORO-2-PHENYL-BUT-2-ENAL
• Synonyms: 3-CHLORO-3-TRIFLUOROMETHYL-2-PHENYLACROLEINE;3-CHLORO-3-TRIFLUOROMETHYL-2-PHENYL-PROPEN-2-AL;3-CHLORO-4,4,4-TRIFLUORO-2-PHENYL-BUT-2-ENAL
• CAS NO: 119197-25-0
• Molecular Formula: C₁₀H₆ClF₃O
• Molecular Weight: 234.6
• Mol File: 119197-25-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-CHLORO-4,4,4-TRIFLUORO-2-PHENYL-BUT-2-ENAL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4,4,4-TRIFLUORO-2-PHENYL-BUT-2-ENAL(119197-25-0)
• EPA Substance Registry System: 3-CHLORO-4,4,4-TRIFLUORO-2-PHENYL-BUT-2-ENAL(119197-25-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 119197-25-0(Hazardous Substances Data)

Upstream product

• 350-92-5 1,1,1-Trifluoro-3-phenylpropan-2-one 
• 68-12-2 N,N-dimethyl-formamide 
• 766-04-1 benzyllithium 

Downstream Products

• 149508-60-1 2-phenyl-3-ethylthio-4,4,4-trifluoromethyl-but-2-en-1-al 
• 136000-11-8 (Z)-2-phenyl-3-ethylthio-4,4,4-trifluoromethyl-but-2-en-1-al 
• 136000-12-9 (E)-2-phenyl-3-ethylthio-4,4,4-trifluoromethyl-but-2-en-1-al 
• 910618-49-4 α-phenyl-2-(trifluoromethyl)thiazolidine-2-acetaldehyde 
• 772-62-3 3,3,3-trifluoro-1-phenylpropyne 
• 34091-69-5 [(1E)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene 
• 34093-70-4 (Z)-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)benzene 
• 709-21-7 3,3,3-trifluoro-1-phenylpropan-1-one 
• 142820-53-9 4,4,4-Trifluoro-2-phenyl-butyraldehyde 
• 166657-66-5 (E)-3-Chloro-4,4,4-trifluoro-2-phenyl-but-2-en-1-ol 
• 131124-01-1 (Z)-4,4,4-Trifluoro-3-mercapto-2-phenyl-but-2-enal 
• 133205-47-7 3-phenyl-4-(trifluoromethyl)quinoline 
• 14468-40-7 2-(trifluoromethyl)-1,3-benzothiazole 
• 133205-46-6 3-phenyl-2-trifluoromethyl-1,5-benzothiazepine 

Relevant articles and documents

NOVEL THIOPHENE DERIVATIVES

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

Preparation of pyrrole-2-carboxylates with electron-withdrawing groups at the 4-position

Reaction of α-trifluoromethyl, α-cyano, and α-ethoxycarbonyl alkenyl sulfones with ethyl isocyanoacetate in the presence of a base gave 4- substituted pyrrole-2-carboxylates in moderate to good yields.

Reactivity of β-(trifluoromethyl) acroleins towards primary alkyl (or aryl) amines: synthesis of trifluoromethyl)-1-aza-1,3-dienes and secondary (trifluoromethyl) allylamines

Vilsmeier's reaction on trifluoroketones leads to β-chloro-β(trifluoromethyl)acroleins.The addition of primary alkyl- or aryl-amines to these acroleins leads in all cases to the formation of stable (trifluoromethyl)-1-aza-1,3-dienes which can be transform