119222-40-1 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 10 carbon (C), 10 hydrogen (H), 1 fluorine (F), 5 nitrogen (N), and 1 oxygen (O) atoms.
Explanation
This describes the specific arrangement of atoms and functional groups in the molecule. The compound is a triazole derivative with a substituted carboxamide group and an amino group attached to a fluorophenylmethyl moiety.
3. Triazole Derivative
Explanation
The compound is derived from a triazole, which is a five-membered ring containing three nitrogen atoms and two carbon atoms. Triazoles are commonly found in various chemical and pharmaceutical applications.
4. Substituted Carboxamide Group
Explanation
A carboxamide group (-CONH2) is present in the molecule, with one of the hydrogen atoms replaced by a substituent, in this case, the 1,2,3-triazole ring.
Explanation
An amino group is attached to the fluorophenylmethyl moiety, which is a part of the molecule that contains a fluorine atom bonded to a phenyl ring.
Explanation
This part of the molecule consists of a phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a fluorine atom at the 4th position and a methyl group (-CH3) attached to it.
Explanation
Due to its unique structure and functional groups, the compound may have potential applications in the field of medicinal chemistry, particularly in the development of pharmaceuticals and bioactive molecules. However, further research and experimentation are required to explore its specific properties, uses, and potential biological activities.
Explanation
To fully understand the properties, uses, and potential biological activities of 1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-[(4-fluorophenyl)methyl]-, additional research and experimentation are necessary. This may include studying its chemical reactivity, stability, solubility, and interactions with biological targets.
Structure
1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-[(4-fluorophenyl)methyl]-
Amino Group
-NH2
Fluorophenylmethyl Moiety
(4-fluorophenyl)methyl
Potential Applications
Medicinal Chemistry, Pharmaceutical Development, Bioactive Molecules
Further Investigation
Research and Experimentation
Check Digit Verification of cas no
The CAS Registry Mumber 119222-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,2,2 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 119222-40:
(8*1)+(7*1)+(6*9)+(5*2)+(4*2)+(3*2)+(2*4)+(1*0)=101
101 % 10 = 1
So 119222-40-1 is a valid CAS Registry Number.
119222-40-1Relevant articles and documents
New amino derivatives of 1,2,3-triazolo[4,5-d]pyrimidines and their affinity towards A1 and A(2A) adenosine receptors
Betti, Laura,Biagi, Giuliana,Giannaccini, Gino,Giorgi, Irene,Livi, Oreste,Lucacchini, Antonio,Manera, Clementina,Scartoni, Valerio
, p. 867 - 875 (1999)
Starting from the appropriate azides (4-chlorobenzyl-, 2- thiophenemethyl-, 2-fluorobenzyl-, and 4-fluorobenzylazides) in which the variation of the substituent is at the basis of the four series of derivatives (a-d), the 7-aminosubstituted 1,2,3-triazolo[4,5-d]pyrimidines 4 were prepared by a well known synthetic route. The biological activity of compounds 4 was expected on the basis of the presence of particular substituents on N(7), and these substituents were introduced by the reaction of the 7 lactamic carbonyl function, present on precursors 3, with cycloalkyl-, aralkyl- and arylamines. Radioligand binding assays at bovine brain adenosine A1 and A(2A) receptors showed that some compounds possessed a high affinity and selectivity for the A1 receptor subtype. Furthermore, biological results indicated that the p-chlorobenzyl substituent lowered receptor binding, compared with the previously prepared benzyl and 2-chlorobenzyl derivatives, suggesting certain particular steric requirements of the lipophilic region which interacts with the benzyl substituent. The thiophenemethyl substituent conferred more activity than the benzyl one. The presence of a fluorine atom on the benzyl group determined a high affinity, especially when it was in the ortho position. Compounds 4c.1 (R = 2-fluorobenzyl, R' = cyclopentyl, Ki = 10.5 nM), 4c.2 (R = 2-fluorobenzyl, R' = cyclohexyl, Ki = 19.5 nM) and 4d.1 (R = 4- fluorobenzyl, R' = cyclopentyl, Ki = 26 nM) were the most active for A1 receptors.
