119267-74-2

Basic information

• Product Name: 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate
• Synonyms: 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate
• CAS NO: 119267-74-2
• Molecular Weight: 323.175
• Mol File: 119267-74-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate(119267-74-2)
• EPA Substance Registry System: 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate(119267-74-2)

Safety Data

• Hazardous Substances Data: 119267-74-2(Hazardous Substances Data)

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 89-98-5 2-chloro-benzaldehyde 
• 446-52-6 2-Fluorobenzaldehyde 
• 100-52-7 benzaldehyde 
• 60229-71-2 (2-bromophenyl)methylene diacetate 
• 104-88-1 4-chlorobenzaldehyde 
• 7401-52-7 1,1-diacetoxy-1-(2-methoxyphenyl)methane 
• 13086-95-8 1,1-diacetoxy-1-(2-chlorophenyl)methane 
• 887138-02-5 2-fluorobenzaldehyde-1,1-diacetate 
• 581-55-5 benzylidene 1,1-diacetate 
• 4254-20-0 4,4'-dichlorobenzoin 
• 75-36-5 acetyl chloride 

Downstream Products

• 51490-05-2 1,2-bis(4-chlorophenyl)ethanone 
• 115-10-6 Dimethyl ether 
• 5406-33-7 4-chlorobenzyl acetate 
• 3686-66-6 sodium p-chlorobenzoate 

Relevant articles and documents

Selective Synthesis of Acylated Cross-Benzoins from Acylals and Aldehydes via N-Heterocyclic Carbene Catalysis

The utility of acylals as building blocks for selective cross-benzoin synthesis was explored in this study. The synthesis of α-acetoxyketones (O-acyl cross-benzoins) was achieved via selective N-heterocyclic carbene-catalyzed cross-benzoin reactions using acylals as aldehyde equivalents. Thus, the combination of ortho-substituted phenyl acylals and aromatic/aliphatic aldehydes as coupling substrates using bicyclic triazolium salts as precatalysts and potassium carbonate as a base in THF at reflux temperature selectively yielded O-acyl cross-benzoins.

Hypervalent Iodine Mediated C-C Double Bond Activation: A Cascade Access to α-Keto Diacetates from Readily Available Cinnamic Acids

The reaction of cinnamic acids with (diacetoxyiodo)benzene in 1,2-dichloroethane in the presence of sulfuric acid provides an easy and direct access to the α-keto diacetate framework. This hypervalent iodine mediated oxidative reaction involves a tandem sequence of aryl migration, insertion of an oxygen atom, decarboxylation and diacetoxylation. A reaction mechanism is proposed and discussed in light of control experiments.