1192755-14-8

Basic information

• Product Name: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan
• Synonyms: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan;Benzofuran-7-boronic acid pinacol ester;7-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzofuran;2-(1-benzofuran-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(Benzofuran-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1192755-14-8
• Molecular Formula: C14H17BO3
• Molecular Weight: 244.09398
• Mol File: 1192755-14-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan(1192755-14-8)
• EPA Substance Registry System: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan(1192755-14-8)

Safety Data

• Hazardous Substances Data: 1192755-14-8(Hazardous Substances Data)

Usage

Description

2-(Benzofuran-7-YL)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, also known as Benzofuran-7-boronic Acid Pinacol Ester, is an organic compound that serves as a reagent in the synthesis of various chemical compounds. It is characterized by its benzofuran core and a boron-containing functional group, which makes it a versatile building block in organic chemistry.

Uses

Used in Pharmaceutical Industry:
2-(Benzofuran-7-YL)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a synthetic reagent for the preparation of 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group. These derivatives are of significant interest due to their potential applications in the treatment of hyper-proliferative disorders, such as cancer.
In the synthesis of these bioactive compounds, Benzofuran-7-boronic Acid Pinacol Ester plays a crucial role in the formation of the desired molecular structure, which can modulate various cellular signaling pathways and exhibit inhibitory effects on tumor growth and progression.
Additionally, the compound can be utilized in the development of novel drug delivery systems to enhance the bioavailability and therapeutic outcomes of the synthesized compounds. By employing various organic and metallic nanoparticles as carriers, the delivery, efficacy, and chemo-sensitivity of these compounds can be improved, particularly in cases of drug resistance.