1192875-03-8 Usage
Description
(Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile, with the molecular formula C10H6ClF, is a chemical compound that presents itself as a yellow to orange liquid with a pungent odor. It is recognized for its potent inhibitory activity against bacterial and fungal pathogens, making it a valuable compound in various applications.
Uses
Used in Pharmaceutical Synthesis:
(Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows for the creation of a wide range of medicinal compounds, contributing to the development of new treatments and therapies.
Used in Agrochemical Production:
In the agrochemical industry, (Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile is utilized as a starting material for the production of pesticides and other agricultural chemicals. Its potent antimicrobial properties make it a valuable asset in protecting crops from diseases and pests, thereby increasing agricultural productivity.
Used in Material Science:
(Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile has been studied for its potential use in the development of new materials. Its chemical properties make it a promising candidate for the creation of innovative materials with unique characteristics, such as enhanced strength, durability, or resistance to environmental factors.
Used as a Building Block for Synthesis:
(Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile also serves as a building block for the synthesis of various functionalized compounds. Its versatile structure allows for the creation of a multitude of chemical products, further expanding its applications across different industries.
Safety Precautions:
Due to its toxic and irritating nature, (Z)-3-chloro-3-(3-fluorophenyl)acrylonitrile should be handled with caution. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be followed when working with this compound to minimize the risk of exposure and ensure the safety of those involved in its production and use.
Check Digit Verification of cas no
The CAS Registry Mumber 1192875-03-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,2,8,7 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1192875-03:
(9*1)+(8*1)+(7*9)+(6*2)+(5*8)+(4*7)+(3*5)+(2*0)+(1*3)=178
178 % 10 = 8
So 1192875-03-8 is a valid CAS Registry Number.
1192875-03-8Relevant articles and documents
3-halo-3-aryl acrylonitrile and preparation method thereof
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Paragraph 0029; 0047-0049, (2018/05/16)
The invention discloses 3-halo-3-aryl acrylonitrile and a preparation method thereof. The method comprises the following steps: dissolving alkyne nitrile into a first substance comprising acetic acid,and adding alkaline metal halide salt to obtain a react
An Improved Convergent Synthesis of AZD7762: A One-Pot Construction of a Highly Substituted Thiophene at the Multikilogram Scale
Ball, Matthew,Jones, Martin F.,Kenley, Fiona,Pittam, J. David
, p. 310 - 316 (2017/03/24)
A multikilogram synthesis of AZD7762 has been achieved using a highly convergent route employing two efficient telescoped sequences to generate the key intermediates. Aminothiophene 11 is formed in a four-step, one-pot addition-elimination-cyclization sequence from cinnamonitrile 9, constructing the trisubstituted thiophene ring with the desired API substitution pattern in place. Cinnamonitrile 9 is derived by elaboration of 3-fluoroacetophenone. Generation of the urea function, followed by deprotection, affords AZD7762 in 49% yield over 5 isolated stages from chiral piperidine 5, a 5-fold increase in yield versus the first generation route, reducing the starting material burden and eliminating the previous requirement for metal-mediated couplings and chromatography.
