1193-68-6 Usage
Description
(3aR,7aR)-rel-octahydro-1H-Indole (Relative struc) is a heterocyclic compound belonging to the indole class, characterized by a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. This specific compound features a unique stereochemistry with R configurations at the 3a and 7a positions. Its relative structure is essential in determining its physical and chemical properties, as well as its interactions with other molecules. It is a significant building block in organic synthesis and holds potential applications across various industrial sectors.
Uses
Used in Pharmaceutical Synthesis:
(3aR,7aR)-rel-octahydro-1H-Indole (Relative struc) is used as a key intermediate in the synthesis of pharmaceuticals due to its diverse chemical reactivity and biological activity. Its unique stereochemistry allows for the development of new drugs with specific therapeutic effects.
Used in Agrochemical Development:
In the agrochemical industry, (3aR,7aR)-rel-octahydro-1H-Indole (Relative struc) is utilized as a precursor in the creation of novel agrochemicals, such as pesticides and herbicides, that can target specific pests or weeds while minimizing environmental impact.
Used in Material Science:
(3aR,7aR)-rel-octahydro-1H-Indole (Relative struc) is employed in material science for the development of new materials with unique properties. Its versatile chemical structure allows for the engineering of materials with tailored characteristics for various applications, such as in electronics, coatings, or advanced composites.
Check Digit Verification of cas no
The CAS Registry Mumber 1193-68-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1193-68:
(6*1)+(5*1)+(4*9)+(3*3)+(2*6)+(1*8)=76
76 % 10 = 6
So 1193-68-6 is a valid CAS Registry Number.
1193-68-6Relevant articles and documents
Hexafluoroisopropanol: A powerful solvent for the hydrogenation of indole derivatives. Selective access to tetrahydroindoles or cis-fused octahydroindoles
Clarisse, Damien,Fenet, Bernard,Fache, Fabienne
experimental part, p. 6587 - 6594 (2012/09/08)
Pd/C in HFIP was used to hydrogenate indole derivatives under relatively mild conditions, leading to potential synthetic intermediates of bioactive compounds. Depending on their substitution, tetrahydroindoles or octahydroindoles could selectively be obtained.
A Stereoselective Synthesis of (+/-)-trans-Cycloalkanopiperidines and Cycloalkanopyrrolidines via Hydroboration
Brown, Herbert C.,Salunkhe, Ashok M.
, p. 1265 - 1268 (2007/10/02)
A highly stereoselective synthesis of trans-cycloalkanopiperidines and cycloalkanopyrrolidines has been achieved via hydroboration of bromocycloalkenes with dichloroboranes.The intermediate bromocycloalkylboronic acids were converted into azidocycloalkylboronates.Addition of two equivalents of boron trichloride in dichloromethane generated dichloroboranes which, by an intramolecular cyclisation gave intermediates 11.These can be readily hydrolyzed to get the corresponding important nitrogen heterocycles in good yields and excellent stereochemical purities.
DIASTEREOSELECTIVE SYNTHESIS OF BICYCLIC AMINO ACIDS VIA RING CONTRACTION OF α-CHLOROLACTAMS
Henning, R.,Urbach, H.
, p. 5339 - 5342 (2007/10/02)
Bicyclic lactams were converted to their α-chloro-derivatives and subjected to ring contraction under basic conditions to give bicyclic acids in diasteroselective fashion.
