1193488-83-3

Basic information

• Product Name: 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid cyclopropylmethoxy-amide
• Synonyms: 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid cyclopropylmethoxy-amide
• CAS NO: 1193488-83-3
• Molecular Weight: 508.344
• Mol File: 1193488-83-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid cyclopropylmethoxy-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid cyclopropylmethoxy-amide(1193488-83-3)
• EPA Substance Registry System: 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid cyclopropylmethoxy-amide(1193488-83-3)

Safety Data

• Hazardous Substances Data: 1193488-83-3(Hazardous Substances Data)

Upstream product

• 1193488-04-8 5-(4-bromo-2-fluoro-phenylamino)-2,2-dimethyl-7-oxo-3a,7,8,8a-tetrahydro-1,3-dioxa-7a-aza-cyclopenta[a]indene-4-carboxylic acid 
• 75647-90-4 O-cyclopropylmethyl-hydroxylamine 

Downstream Products

• 1193488-05-9 7-(4-bromo-2-fluoro-phenylamino)-1,2-dihydroxy-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid cyclopropylmethoxy-amide 

Relevant articles and documents

Heterocyclic Compounds as MEK Inhibitors

The present invention relates to compounds of formula I and pharmaceutically acceptable salts. These compounds can act as potential MEK inhibitors in the treatment of hyperproliferative diseases, like cancer and inflammation. The present invention also reveals methods of preparation thereof.