119391-56-9 Usage
General Description
MAChR-IN-1 is a chemical compound that acts as a positive allosteric modulator of the muscarinic acetylcholine receptor M1. It demonstrates high selectivity for M1 receptors and enhances the binding of acetylcholine at these sites. This modulation of M1 receptor activity has potential therapeutic implications for the treatment of neurodegenerative diseases, as M1 receptors are involved in cognitive function and memory processes. MAChR-IN-1 may be useful for studying the specific role of M1 receptors in neurological disorders and for developing novel treatments targeting these receptors. Further research is required to fully understand the pharmacological properties and therapeutic potential of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 119391-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,3,9 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119391-56:
(8*1)+(7*1)+(6*9)+(5*3)+(4*9)+(3*1)+(2*5)+(1*6)=139
139 % 10 = 9
So 119391-56-9 is a valid CAS Registry Number.
119391-56-9Relevant articles and documents
Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist
Wilson,Dannals,Ravert,Frost,Wagner Jr.
, p. 1057 - 1062 (2007/10/02)
A series of halogenated racemic analogues of dexetimide (1) was synthesized and their affinity for the muscarinic cholinergic receptor measured. One analogue, 4-iododexetimide (21), was efficiently labeled with 125I and 123I at high
