119492-83-0

Basic information

• Product Name: 2-(4-Methoxyphenyl)-5-phenylfuran
• Synonyms: 2-(4-Methoxyphenyl)-5-phenylfuran
• CAS NO: 119492-83-0
• Molecular Weight: 234.298
• Mol File: 119492-83-0.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-(4-Methoxyphenyl)-5-phenylfuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)-5-phenylfuran(119492-83-0)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)-5-phenylfuran(119492-83-0)

Safety Data

• Hazardous Substances Data: 119492-83-0(Hazardous Substances Data)

Upstream product

• 119492-74-9 4-Phenyl-1-p-tolyl-but-3-yn-1-one 
• 17113-33-6 2-phenylfuran 
• 106-38-7 para-bromotoluene 
• 852211-44-0 4-(4-methylphenyl)-1-phenylbut-3-yn-1-one 
• 34679-27-1 gold(I) phenylacetylide 
• 102-96-5 (2-nitroethenyl)benzene 
• 122-00-9 para-methylacetophenone 
• 1866-39-3 4-methylcinnamic acid 
• 98-86-2 acetophenone 
• 100-42-5 styrene 
• 1265154-01-5 (Z)-4-(4-methylphenyl)-1-phenylbut-1-en-3-yn-1-yl acetate 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 1075-47-4 4-methylphenylglyoxal 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Ruthenium(ii)-catalyzed chemoselective deacylative annulation of 1,3-diones with sulfoxonium ylides: Via C-C bond activation

The first successful example of deacylative annulation of 1,3-diones with sulfoxonium ylides was achieved through Ru(ii)-catalyzed C-C bond activation. The excellent chemoselectivity and broad substrate scope render this method a practical and versatile approach for the preparation of (hetero)aryl and alkenyl substituted furans, which are valuable units in many biologically active compounds and functional materials. A preliminary mechanistic study reveals that this process involves a deacylative α-ruthenation to generate key alkyl Ru(ii) intermediates with the release of a benzoic acid fragment.

Decarboxylative Suzuki-Miyaura coupling of (hetero)aromatic carboxylic acids using iodine as the terminal oxidant

A novel methodology for the decarboxylative Suzuki-Miyaura-type coupling has been established. This process uses iodine or a bromine source as both the decarboxylation mediator and the terminal oxidant, thus avoiding the need for stoichiometric amounts of transition metal salts previously required. Our new protocol allows for the construction of valuable biaryl architectures through the coupling of (hetero)aromatic carboxylic acids with arylboronic acids. The scope of this decarboxylative Suzuki reaction has been greatly diversified, allowing for previously inaccessible non-ortho-substituted aromatic acids to undergo this transformation. The procedure also benefits from low catalyst loadings and the absence of stoichiometric transition metal additives.

Epoxy-containing skeleton nitrile compound and synthesis method thereof

The invention relates to an epoxy-containing skeleton nitrile compound as shown in the following formula (4) and a synthesis method thereof. The synthesis method adopts the following reaction route: FORMULA, and comprises the following steps: S1: reacting a compound of a formula (1) with a compound of formula (2) in an organic solvent in the presence of a palladium catalyst, an organic ligand, anoxidizing agent and an acidic compound, performing post-treatment after finishing reaction to obtain a compound of formula (3); and S2: performing self-cyclization reaction on the compound of formula(3) in the organic solvent in the presence of the oxidizing agent, performing post-treatment after finishing reaction to obtain a compound of formula (4). The method creatively optimizes multiple technical features in each step so as to provide a novel synthesis method and synthesis route for preparation of such compounds and have excellent industrial prospects and potential application values.