119620-25-6

Basic information

• Product Name: 1,1-dimethylethyl 4-fluoro-3-hydroxy-3-methyl-2-(phenylmethoxy)butanoate
• CAS NO: 119620-25-6
• Molecular Weight: 298.355
• Mol File: 119620-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl 4-fluoro-3-hydroxy-3-methyl-2-(phenylmethoxy)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl 4-fluoro-3-hydroxy-3-methyl-2-(phenylmethoxy)butanoate(119620-25-6)
• EPA Substance Registry System: 1,1-dimethylethyl 4-fluoro-3-hydroxy-3-methyl-2-(phenylmethoxy)butanoate(119620-25-6)

Safety Data

• Hazardous Substances Data: 119620-25-6(Hazardous Substances Data)

Upstream product

• 430-51-3 1-fluoro-2-propanone 
• 119620-31-4 benzyloxyacetic acid t-butyl ester 

Relevant articles and documents

Purification and Inhibition of Spinach &α,&β-Dihydroxyacid Dehydratase

The α,β-dihydroxyacid dehydratase (E.C. 4.2.1.9) responsible for the production of α-oxoisovaleric acid in the valine biosynthetic pathway has been purified from spinach leaves.Its properities are similar to those given in a previous report using a less pure preparation.Its monomer mass is estimated to be 55 kDa.Evidence for an enol intermediate in the reaction mechanism has been obtained by a deuterium labeling study.Several inhibitors have been screened against the enzyme.Four of particular effectiveness are 4-fluoro-3,3-dihydroxyisovaleric acid, 1-hydroxy-1-isobutanesulfonic acid, N,N-dimethylglycine N-oxide, and 2-fluoro-3,3-dimethylacrylic acid.As an enol analogue, the latter compound gives further evidence for enol itermediate.