119680-05-6Relevant articles and documents
Bioreductive deprotection of 4-nitrobenzyl group on thymine base in oligonucleotides for the activation of duplex formation
Saneyoshi, Hisao,Hiyoshi, Yuki,Iketani, Koichi,Kondo, Kazuhiko,Ono, Akira
, p. 5632 - 5635 (2015)
Oligonucleotides containing 4-O-(4-NO2-benzyl)thymine residues were synthesized to assess potential prodrug-type action against hypoxic cells. These modified oligonucleotides were incapable of stable duplex formation under non-hypoxic condition