1196968-94-1Relevant articles and documents
Potent biphenyl- and 3-phenyl pyridine-based inhibitors of acetyl-CoA carboxylase
Haque, Tasir S.,Liang, Ningning,Golla, Rajasree,Seethala, Ramakrishna,Ma, Zhengping,Ewing, William R.,Cooper, Christopher B.,Pelleymounter, Mary Ann,Poss, Michael A.,Cheng, Dong
scheme or table, p. 5872 - 5876 (2010/07/04)
We report the synthesis and enzymatic evaluation of potent inhibitors of acetyl-CoA carboxylases (ACCs) containing biphenyl or 3-phenyl pyridine cores. These compounds inhibit both ACC1 and ACC2, or are moderately selective for either enzyme, depending on
