1196985-65-5 Usage
Description
4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is an organic compound characterized by its unique chemical structure, which features a phenol group with a methyl substitution at the 4th position and a 1,3,2-dioxaborolan-2-yl group at the 3rd position. 4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is known for its potential applications in various chemical and pharmaceutical processes due to its versatile functional groups.
Uses
Used in Pharmaceutical Industry:
4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is used as a key intermediate in the synthesis of NIK inhibitors for the pharmaceutical industry. These inhibitors play a crucial role in modulating the NF-κB signaling pathway, which is involved in various cellular processes, including inflammation, immune response, and cell survival. By targeting NIK, these inhibitors can potentially be used to treat conditions associated with dysregulated NF-κB signaling, such as autoimmune diseases, chronic inflammation, and cancer.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a versatile building block for the development of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable starting material for the synthesis of complex molecules with diverse applications, such as pharmaceuticals, agrochemicals, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1196985-65-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,9,8 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1196985-65:
(9*1)+(8*1)+(7*9)+(6*6)+(5*9)+(4*8)+(3*5)+(2*6)+(1*5)=225
225 % 10 = 5
So 1196985-65-5 is a valid CAS Registry Number.
1196985-65-5Relevant articles and documents
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase α inhibitors
Kuramochi, Kouji,Fukudome, Keishi,Kuriyama, Isoko,Takeuchi, Toshifumi,Sato, Yoshihiro,Kamisuki, Shinji,Tsubaki, Kazunori,Sugawara, Fumio,Yoshida, Hiromi,Mizushina, Yoshiyuki
experimental part, p. 7227 - 7238 (2010/03/03)
Herein, we describe the synthesis and structure-activity relationships of dehydroaltenusin derivatives as inhibitors of a mammalian DNA polymerase α. We have newly synthesized nine dehydroaltenusin derivatives modified at the side chains or benzoquinone m
