1197653-62-5Relevant articles and documents
Bis(2,2,2-trifluoroethyl) carbonate as a condensing agent in one-pot parallel synthesis of unsymmetrical aliphatic ureas
Bogolubsky, Andrey V.,Moroz, Yurii S.,Mykhailiuk, Pavel K.,Granat, Dmitry S.,Pipko, Sergey E.,Konovets, Anzhelika I.,Doroschuk, Roman,Tolmachev, Andrey
supporting information, p. 303 - 308 (2014/06/24)
One-pot parallel synthesis of unsymmetrical aliphatic ureas was achieved with bis(2,2,2-trifluoroethyl) carbonate. The procedure worked well for both the monosubstituted and functionalized alkyl amines and required no special conditions (temperature control, order, or rate of addition). A library of 96 diverse ureas was easily synthesized.
