1198166-34-5Relevant articles and documents
Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist
Koura, Minoru,Yamaguchi, Yuki,Kurobuchi, Sayaka,Sumida, Hisashi,Watanabe, Yuichiro,Enomoto, Takashi,Matsuda, Takayuki,Okuda, Ayumu,Koshizawa, Tomoaki,Matsumoto, Yuki,Shibuya, Kimiyuki
supporting information, p. 3436 - 3446 (2016/07/21)
Our research found that the 2-hydroxyacetophenone derivative is an outstanding linker between the 1,1-bistrifluoromethylcarbinol moiety and the imidazolidine-2,4-dione moiety to enhance the potency and β-selectivity of liver X receptor (LXR) agonist in ou