119866-67-0

Basic information

• Product Name: (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester
• Synonyms: (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester
• CAS NO: 119866-67-0
• Molecular Weight: 431.532
• Mol File: 119866-67-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester(119866-67-0)
• EPA Substance Registry System: (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 2-cyano-ethyl ester(119866-67-0)

Safety Data

• Hazardous Substances Data: 119866-67-0(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 7535-56-0 N-t-butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester 
• 119866-76-1 Boc-Leu-OCet 

Downstream Products

• 84047-92-7 Boc-Tyr-Gly-Gly-Phe-Leu-NHNH₂ 
• 58822-25-6 Leu-enkephalin 

Relevant articles and documents

PROTECTION OF THE CARBOXY GROUP IN THE FORM OF THE 2-CYANOETHYL ESTERS IN SYNTHESIS OF PEPTIDES

With the aim of studying the suitability of the 2-cyano group for the protection of carboxylic functions in peptide synthesis, we have obtained the 2-cyanoethyl esters of a number of amino acids and have studied their behavior under the conditions of peptide synthesis.The synthesis of the pentapeptide leucine-enkephalin has been performed with the use of 2-cyanoethyl protection for C-terminal carboxy groups throughout.The physicochemical characteristics of the compounds synthesized are given.