119906-55-7

Basic information

• Product Name: ((Z)-1-Benzyl-5-trimethylsilanyl-pent-2-en-4-ynyl)-carbamic acid tert-butyl ester
• CAS NO: 119906-55-7
• Molecular Weight: 343.541
• Mol File: 119906-55-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((Z)-1-Benzyl-5-trimethylsilanyl-pent-2-en-4-ynyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((Z)-1-Benzyl-5-trimethylsilanyl-pent-2-en-4-ynyl)-carbamic acid tert-butyl ester(119906-55-7)
• EPA Substance Registry System: ((Z)-1-Benzyl-5-trimethylsilanyl-pent-2-en-4-ynyl)-carbamic acid tert-butyl ester(119906-55-7)

Safety Data

• Hazardous Substances Data: 119906-55-7(Hazardous Substances Data)

Upstream product

• 103127-53-3 N-tert-butyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 42134-49-6 (3-trimethylsilyl-2-propynyl)triphenylphosphonium bromide 

Relevant articles and documents

SYNTHESIS OF α-AMINO ACIDS WITH β,γ-UNSATURATED SIDE CHAINS

α-Amino acids with allenyl, vinyl and acetylenic side chains can be synthesized using non-enolate based strategies.The ester enolate-Claisen rearrangement applied to propargylic esters of N-protected α-amino acids is of limited utility since only poor yields of allenic product are obtained with the N-Boc glycine esters, the system which give the most reproducible results.However, α-allenyl-α-amino acids that are fully functionalized on the α-carbon are available through the agency of 4-allenyl-2-phenyloxazolones 4 ( obtained from propargyl esters of N-benzoyl protected amino acids via cyclization and Claisen rearrangement ) provided that Meerwein's reagent is used to facilitate hydrolysis of the benzamide function in 5.A variety of α-substituted glycinates, including those with α-vinyl and α-acetylenic functions, can be prepared using a two step sequence involving condensation of the cationic glycine synthon 22 with various organomagnesium reagents, followed by hydrolysis.