120-89-8 Usage
Description
Parabanic acid, an imidazolidinone derivative, is a white crystalline solid with the chemical structure of imidazolidine substituted by oxo groups at positions 2, 4, and 5. It is recognized for its significance as a marker of free radical reactions in biological systems.
Uses
1. Used in Medical Applications:
Parabanic acid is used as a marker for monitoring free radical activity in vivo. This application aids in evaluating the effectiveness of pharmacological therapies involving radical scavengers, which are crucial for understanding and managing various diseases and conditions related to oxidative stress.
2. Used in Chemical Synthesis:
Parabanic acid serves as a valuable synthetic intermediate in the creation of various chemical compounds. Its versatile structure allows it to be a key component in the synthesis of numerous derivatives and complexes.
a. Used in Enantiospecific Assembly:
Parabanic acid is used as a reactant for the enantiospecific assembly of homochiral, hexanuclear palladium complexes. These complexes have potential applications in catalysis and other areas of chemistry.
b. Used in Mitsunobu Reactions:
It is also utilized in Mitsunobu reactions, which are a class of chemical reactions that involve the inversion of stereochemistry and the formation of new carbon-heteroatom bonds.
c. Used in Quantitative Cascade Condensation Reactions:
Parabanic acid is employed in quantitative cascade condensation reactions, which are multi-step processes that result in the formation of complex molecular structures.
d. Reactant for Synthesis of Pyridine Derivatives:
It is used as a reactant in the synthesis of pyridine derivatives, which are important compounds in the field of organic chemistry and have various applications, including pharmaceuticals and agrochemicals.
e. Reactant for Synthesis of Nitroesters:
Parabanic acid is used in the synthesis of nitroesters, which are compounds that find use in the production of explosives, propellants, and other industrial applications.
f. Reactant for Synthesis of Parabanic Acid Derivatives:
It is also used as a reactant for the synthesis of its own derivatives, which can have specialized applications in various fields, depending on their specific properties and structures.
Check Digit Verification of cas no
The CAS Registry Mumber 120-89-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120-89:
(5*1)+(4*2)+(3*0)+(2*8)+(1*9)=38
38 % 10 = 8
So 120-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C3H2N2O3/c6-1-2(7)5-3(8)4-1/h(H2,4,5,6,7,8)
120-89-8Relevant articles and documents
Gas-solid reactions of single crystals: A study of reactions of NH 3 and NO2 with single crystalline organic substrates by infrared microspectroscopy
Jenkins, Samantha L.,Almond, Matthew J.,Atkinson, Samantha D.M.,Hollins, Peter,Knowles, John P.
, p. 1131 - 1139 (2005)
Reaction of single crystals of benzoic and trans-cinnamic acids with 200 Torr pressure of ammonia gas in a sealed glass bulb at 20 °C generates the corresponding ammonium salts; there is no sign of any 1:2 adduct as has been reported previously for related systems. Isotopic substitution using ND 3 has been used to aid identification of the products. Adipic acid likewise reacts with NH3 gas to form a product in which ammonium salts are formed at both carboxylic acid groups. Reaction of 0.5 Torr pressure of NO2 gas with single crystals of 9-methylanthracene and 9-anthracenemethanol in a flow system generates nitrated products where the nitro group appears to be attached at the 10-position, i.e. the position trans to the methyl or methoxy substituent on the central ring. Isotopic substitution using 15NO2 has been used to confirm the identity of the bands arising from the coordinated NO2 group. The products formed when single crystals of hydantoin are reacted with NO2 gas under similar conditions depend on the temperature of the reaction. At 20 °C, a nitrated product is formed, but at 65 °C this gives way to a product containing no nitro groups. The findings show the general applicability of infrared microspectroscopy to a study of gas-solid reactions of organic single crystals.
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Silica Metal Oxide Vesicles Catalyze Comprehensive Prebiotic Chemistry
Mattia Bizzarri, Bruno,Botta, Lorenzo,Pérez-Valverde, Maritza Iveth,Saladino, Raffaele,Di Mauro, Ernesto,García-Ruiz, Juan Manuel
, p. 8126 - 8132 (2018/05/29)
It has recently been demonstrated that mineral self-assembled structures catalyzing prebiotic chemical reactions may form in natural waters derived from serpentinization, a geological process widespread in the early stages of Earth-like planets. We have s
