120157-99-5Relevant articles and documents
PURINE DERIVATIVES WITH ACTIVITY TO THE ADENOSINE A2A RECEPTOR
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Page/Page column 43, (2008/06/13)
A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein U, R1, R2 and R3 are as defined herein.
Synthesis of optically active β,γ-alkynylglycine derivatives
Meffre, Patrick,Gauzy, Laurence,Branquet, Eric,Durand, Philippe,Le Goffic, Francois
, p. 11215 - 11238 (2007/10/03)
Full results on the first synthesis of optically active β,γ-alkynylglycine derivatives from naturally occurring L-serine are described. The methodology uses L-serinal as a key intermediate and allows great versatility in the introduction of N-protective groups and of alkyne substitution. The N-Boc protected β,γ-alkynylglycine derivatives described have ee greater than 90%.
A New Method for the Synthesis of Amides from Amines: Ruthenium Tetroxide Oxidation of N-Protected Alkylamines
Tanaka, Ken-Ichi,Yoshifuji, Shigeyuki,Nitta, Yoshihiro
, p. 3125 - 3129 (2007/10/02)
A simple synthetic method for the preparation of amides from the corresponding primary alkylamines was elaborated using ruthenium tetroxide (RuO4) oxidation as a key step.