1201844-73-6

Basic information

• Product Name: 4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
• Synonyms: 4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
• CAS NO: 1201844-73-6
• Molecular Weight: 289.569
• Mol File: 1201844-73-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline(1201844-73-6)
• EPA Substance Registry System: 4-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline(1201844-73-6)

Safety Data

• Hazardous Substances Data: 1201844-73-6(Hazardous Substances Data)

Upstream product

• 65340-70-7 6-bromo-4-chloroquinoline 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1201841-63-5 N-(2-chloro-5-(4-chloroquinolin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 
• 1201842-34-3 N-(2-chloro-5-(4-(2-methoxy-3-pyridinyl)-6-quinolinyl)-3-pyridinyl)-4-fluorobenzenesulfonamide 
• 1201842-26-3 N-(2-chloro-5-(4-(2-methoxyethoxy)-6-quinolinyl)-3-pyridinyl)-4-fluorobenzenesulfonamide 
• 1201842-13-8 N-(2-chloro-5-(4-(4-isopropylpiperazin-1-yl)quinolin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 
• 1201842-17-2 N-(2-chloro-5-(4-(4-hydroxypiperidin-1-yl)quinolin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 
• 1201842-11-6 N-(2-chloro-5-(4-(piperidin-1-yl)quinolin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 
• 1201843-67-5 N-(2-chloro-5-(4-(4-(pyridin-4-ylmethyl)piperazin-1-yl)quinolin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 

Relevant articles and documents

INHIBITORS OF THE MENIN-MLL INTERACTION

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

N-(5-(QUINOLIN-6-YL)PYRIDIN-3-YL) BENZSULFAMIDE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE THEREOF

The present invention relates to the field of medical technology, and in particular, to a variety of substituted N-(5-(quinolin -6-yl)pyridin -3 -yl) bezsulfamide derivatives represented by formula (1) (groups therein are as defined in the specification).The compounds according to the present invention have favorable anti-tumor activity against human lung cancer, colon cancer, liver cancer, breast cancer and glioblastoma multiforme, which contribute to development of highly effective, low toxic and high specific anti-tumor drugs, and have high value of development. The present invention also relates to a composition, preparation method and use thereof in the preparation of anti-tumor drugs.

INHIBITORS OF PI3 KINASE

The present invention relates to compounds of Formula (I), or a pharmaceutically acceptable salt thereof; methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein Q, X1, X2, R1 and Z are as defined herein.