1201851-44-6Relevant articles and documents
Novel spiro and fused heterocycles from the allylation of indigo
Abdel-Hamid, Mohammed K.,Bremner, John B.,Coates, Jonathan,Keller, Paul A.,Mil?nder, Celia,Torkamani, Yasmine S.,Skelton, Brian W.,White, Allan H.,Willis, Anthony C.
supporting information; experimental part, p. 6947 - 6950 (2010/02/27)
The allylation of indigo results in the one-step synthesis of two unique complex heterocyclic systems: a spiroindoline-pyridoindolone arising from the addition of three allyl moieties and a fused pyridoindolo-azepinoindolone generated from the addition and subsequent cyclisation of two allyl moieties. The structures of these novel heterocycles are assigned unambiguously using extensive NMR experiments and by X-ray crystallographic analysis. The distribution of the products is influenced by the use of thermal versus microwave heating. Crown Copyright