1201905-61-4 Usage
Description
(E)-1-Ethoxyethene-2-ylboronic acid pinacol ester, also known as trans-2-Ethoxyvinylboronic acid pinacol ester, is a boronic ester compound that plays a crucial role in organic synthesis. It is characterized by its ability to participate in various chemical reactions, particularly in the Suzuki-Miyaura cross-coupling process, which is a widely used method for the formation of carbon-carbon bonds.
Uses
Used in Pharmaceutical Industry:
(E)-1-Ethoxyethene-2-ylboronic acid pinacol ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its application in this industry is primarily due to its ability to facilitate the formation of carbon-carbon bonds through the Suzuki-Miyaura cross-coupling reaction, enabling the creation of complex molecular structures with potential therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester is used as a versatile building block for the construction of a wide range of organic molecules. Its reactivity in the Suzuki-Miyaura cross-coupling reaction allows chemists to efficiently synthesize various organic compounds with diverse functional groups and structural features.
Used in the Synthesis of Azaindole and Diazaindoles:
(E)-1-Ethoxyethene-2-ylboronic acid pinacol ester is used as a starting material for the synthesis of azaindole and diazaindole compounds from chloroamino-N-heterocycles. These heterocyclic compounds are of significant interest in medicinal chemistry and drug discovery due to their potential biological activities and applications as pharmaceutical agents.
Used in the Synthesis of Doryanine and its Derivatives:
In the synthesis of doryanine and its derivatives from 2-bromobenzoic acid, (E)-1-Ethoxyethene-2-ylboronic acid pinacol ester serves as a crucial reagent. Doryanine and its derivatives are known for their various biological properties, making them valuable targets for the development of new pharmaceuticals and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1201905-61-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,1,9,0 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1201905-61:
(9*1)+(8*2)+(7*0)+(6*1)+(5*9)+(4*0)+(3*5)+(2*6)+(1*1)=104
104 % 10 = 4
So 1201905-61-4 is a valid CAS Registry Number.
1201905-61-4Relevant articles and documents
Concise synthesis of new bridged-nicotine analogues
Crestey, Franois,Hooyberghs, Geert,Kristensen, Jesper L.
, p. 1417 - 1421 (2012)
This study describes a very efficient strategy for the synthesis of two new bridged-nicotine analogues. Starting from either 4- or 3-chloropyridine the desired tricyclic ring systems are accessed in just three steps in 23% and 40% overall yield, respectively.
1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES
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Page/Page column 173; 178, (2021/07/02)
The present invention relates to lH-pyrrolo[2,3-b]pyridine derivatives and related compounds as BCL-2 inhibitors for treating neoplastic, autoimmune or neurodegenerative diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 162 to 233; examples 1 to 8; table; compound examples cpd-1 to cpd-135; biological examples 1 to 4).
ISOQUINOLINE DERIVATIVES AS PERK INHIBITORS
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Page/Page column 120, (2018/02/17)
The invention is directed to substituted isoquinoline derivatives and uses thereof. Specifically, the invention is directed to compounds according to Formula I and the use of compounds of Formula (I) in treating disease states: (I) wherein R1,
