1201935-36-5

Basic information

• Product Name: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine
• Synonyms: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine;1-(1-methyl-4-piperidinyl)-1H-Pyrazol-4-amine;1-(1-methylpiperidin-4-yl)pyrazol-4-amine
• CAS NO: 1201935-36-5
• Molecular Formula: C₉H₁₆N₄
• Molecular Weight: 180.25014
• EINECS: 200-258-5
• Mol File: 1201935-36-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 335.0±32.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.55±0.10(Predicted)
• CAS DataBase Reference: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(1201935-36-5)
• EPA Substance Registry System: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(1201935-36-5)

Safety Data

• Hazardous Substances Data: 1201935-36-5(Hazardous Substances Data)

Usage

General Description

1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is a chemical compound with the molecular formula C10H16N4. It is a pyrazole derivative and contains a methylpiperidine group. 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is important in medicinal chemistry as it has been found to exhibit selective inhibitory activity on certain enzymes, making it a potential candidate for drug development. Its structure and properties make it suitable for further research and development in the pharmaceutical industry.

Upstream product

• 1201935-35-4 1-methyl-4-(4-nitro-1H-pyrazol-1-yl)piperidine 
• 1201916-87-1 4-(4-nitro-1H-pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 106-52-5 N-methyl-4-hydroxypiperidine 
• 132710-79-3 1-methylpiperidin-4-yl-4-methylbenzenesulfonate 

Downstream Products

• 1201933-99-4 2-((5-chloro-2-((1-(1-methyl-4-piperidyl)pyrazol-4-yl)amino)-4-pyridyl)amino)-N-methoxy-N-methyl-benzamide 
• 1566543-19-8 2-(2-(2-(5-chloro-2-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-ylamino)pyrimidin-4-yl)ethyl)phenyl)propanamide 
• 1453207-62-9 5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine 

Relevant articles and documents

FGFR Inhibitor compounds and uses thereof

The invention relates to FGFR inhibitor compounds and uses thereof. , The application discloses a compound as shown in a formula (I). A compound, or an optical isomer, a geometric isomer, a tautomer or isomer mixture thereof, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The application further relates to the application of the compound in medicine.

JAK1 SELECTIVE KINASE INHIBITOR

Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, that are useful as JAK kinase inhibitors. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula (I), and methods of using such compounds or compositions to treat respiratory conditions (e.g., asthma or COPD).

HETEROCYCLIC COMPOUNDS FOR MEDIATING TYROSINE KINASE 2 ACTIVITY

Heterocyclic compounds shown in Formula (I) suitable for inhibiting or regulating the activity of Janus kinase (JAK), particularly tyrosine kinase 2 (TYK2). The compounds are useful for preventing and/or treating relevant JAK-mediated diseases, such as autoimmune diseases, inflammatory diseases, and cancers.