1202-22-8

Basic information

• Product Name: 4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE
• Synonyms: N-[4-CHLORO-6-(DIMETHYLAMINO)PYRIMIDIN-2-YL]-N,N-DIMETHYLAMINE;4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE;[6-chloro-2-(dimethylamino)pyrimidin-4-yl]-dimethyl-amine;6-chloro-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4-diamine;6-chloro-N2,N2,N4,N4-tetramethyl-pyrimidine-2,4-diamine
• CAS NO: 1202-22-8
• Molecular Formula: C8H13ClN4
• Molecular Weight: 200.67
• Mol File: 1202-22-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 334°Cat760mmHg
• Flash Point: 155.8°C
• Appearance: /
• Density: 1.224g/cm³
• Vapor Pressure: 0.000132mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE(1202-22-8)
• EPA Substance Registry System: 4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE(1202-22-8)

Safety Data

• Hazardous Substances Data: 1202-22-8(Hazardous Substances Data)

Usage

General Description

4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE is a chemical compound consisting of a pyrimidine ring with a chlorine atom at the 4th position and two dimethylamino groups at the 2nd and 6th positions. It is primarily used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. 4-CHLORO-2,6-BIS(DIMETHYLAMINO)PYRIMIDINE is a versatile building block in organic synthesis and is used in the production of drugs such as antiviral and anticancer agents. It can also be used as a reagent in chemical reactions to introduce the pyrimidine ring into other molecules. However, it is important to handle this compound with caution as it may pose health and environmental hazards.

InChI:InChI=1/C8H13ClN4/c1-12(2)7-5-6(9)10-8(11-7)13(3)4/h5H,1-4H3

Upstream product

• 3764-01-0 2,4,6-trichloropyrimidine 
• 124-40-3 dimethyl amine 
• 5734-68-9 4,6-dichloro-N,N-dimethyl-pyrimidin-2-amine 
• 117077-93-7 2,6-dichloro-N,N-dimethylpyrimidin-4-amine 

Downstream Products

• 133939-75-0 N²,N²-dimethyl-N⁴,N⁶-di-p-tolyl-pyrimidine-2,4,6-triyltriamine 

Relevant articles and documents

TRIAMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF CDC25 PHOSPHATASE

The present invention relates to the novel triaminopyrimidine derivatives of formula (I) in which R1, R2, W, R3, R4, and R5 are variable groups. These products have a Cdc25-phosphatase-inhibiting activity. The invention also relates to a process for synth

PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF

The present invention encompasses novel substituted pyrimidine compounds of Formula (I): which act as MCH receptor antagonists. These compounds are useful in pharmaceutical compositions whose use includes prophylaxis or treatment of improving memory function, sleeping and arousal, anxiety, depression, mood disorders, seizure, obesity, diabetes, appetite and eating disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial infarction, binge eating disorders including bulimia, anorexia, mental disorders including manic depression, schizophrenia, delirium, dementia, stress, cognitive disorders, attention deficit disorder, substance abuse disorders and dyskinesias including Parkinson’s disease, epilepsy, and addiction.

Amines useful in producing pharmaceutically active CNS compounds

Disclosed are Δ9(11) -steroids (VI) and amino substituted steroids (XI) which contain an amino group attached to the terminal carbon atom of the C17 -side chain, more particularly amino steroids (Ia and Ib), aromatic steroids (II), Δ16 -steroids (IIIa and IIIb), reduced A-ring steroids (IV), Δ17(20) -steroids (Va and Vb) and Δ9(11) -steroids (VI) which are useful as pharmaceutical agents for treating a number of conditions.