1202-60-4 Usage
Description
(2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid, also known as 2Z-4-chlorocinnamic acid, is a chemical compound with a molecular formula of C10H9ClO2. It is characterized by its trans geometric isomerism and contains a 4-chlorophenyl group and a methylprop-2-enoic acid moiety. This white to off-white crystalline powder is sparingly soluble in water but soluble in organic solvents. (2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid also exhibits anti-inflammatory and antioxidant properties, making it a potential candidate for drug development and research in the medical and pharmaceutical fields.
Uses
Used in Pharmaceutical Synthesis:
(2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, (2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid is utilized in the production of various agrochemicals. Its chemical properties allow it to be incorporated into formulations that can enhance crop protection and improve agricultural yields.
Used in Organic Material Synthesis:
(2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid is also used in the synthesis of organic materials, where its chemical structure contributes to the development of new materials with specific properties for various applications.
Used in Drug Development and Research:
Due to its anti-inflammatory and antioxidant properties, (2Z)-3-(4-chlorophenyl)-2-methylprop-2-enoic acid is a potential candidate for drug development and research in the medical and pharmaceutical fields. Its ability to modulate biological processes makes it a promising compound for the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1202-60-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1202-60:
(6*1)+(5*2)+(4*0)+(3*2)+(2*6)+(1*0)=34
34 % 10 = 4
So 1202-60-4 is a valid CAS Registry Number.
1202-60-4Relevant articles and documents
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Noyce,D.S.,Banitt,E.H.
, p. 4043 - 4047 (1966)
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Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes
Bouillon, Jean-Philippe,Brégent, Thibaud,Poisson, Thomas
supporting information, p. 7688 - 7693 (2020/10/09)
The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.
Microwave-assisted synthesis of the (E)-α-methylalkenoate framework from multifunctionalized allylic phosphonium salts
Meier, Lidiane,Ferreira, Misael,Sa, Marcus M.
, p. 179 - 186 (2012/07/14)
A convenient and general microwave-assisted method for the synthesis of stereochemically defined α-methylalkenoic acids and esters from allylic phosphonium salts in a basic aqueous medium is described. A selective preparation of acids or esters was dependent on the base (NaOH or NaHCO 3) employed in the reaction and could be achieved with good to excellent yields under mild conditions in the absence of hydrides and reducing agents.
