1202236-78-9

Basic information

• Product Name: 2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1202236-78-9
• Molecular Weight: 294.201
• Mol File: 1202236-78-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1202236-78-9)
• EPA Substance Registry System: 2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1202236-78-9)

Safety Data

• Hazardous Substances Data: 1202236-78-9(Hazardous Substances Data)

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 86130-05-4 4-(methoxymethyl)-1,1'-biphenyl 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 5122-94-1 4-biphenylboronic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 2567-29-5 p-phenylbenzyl bromide 
• 361162-22-3 4-tert-butyldimethylsilyloxymethylbiphenyl 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 3218-36-8 4-Phenylbenzaldehyde 
• 40154-51-6 N′-([1,1′-biphenyl]-4-ylmethylene)-4-methylbenzenesulfonohydrazide 

Downstream Products

• 5728-52-9 (4-biphenylyl)acetic acid 

Relevant articles and documents

Ipso- borylation of aryl ethers via Ni-Catalyzed C-OMe Cleavage

A Ni-catalyzed ipso-borylation of aryl ethers via C(sp2)-OMe and C(sp3)-OMe cleavage is described. The transformation is characterized by its wide substrate scope under mild conditions and an exquisite divergence in site selectivity that can be easily switched by selecting the appropriate boron reagent.

Regioselective α-benzylation of 3-iodoazetidine via Suzuki cross-coupling

An efficient protocol for the synthesis of α-benzyl azetidines starting from benzylboronic acid pinacol ester derivatives and 3-iodoazetidine was developed. A wide range of α-benzyl azetidine derivatives were obtained in moderate to good yields with high regioselectivity (>99%).

Photochemical Radical C–H Halogenation of Benzyl N-Methyliminodiacetyl (MIDA) Boronates: Synthesis of α-Functionalized Alkyl Boronates

α-Haloboronates are useful organic synthons that can be converted to a diverse array of α-substituted alkyl borons. Methods to α-haloboronates are limiting and often suffer from harsh reaction conditions. Reported herein is a photochemical radical C-H halogenation of benzyl N-methyliminodiacetyl (MIDA) boronates. Fluorination, chlorination, and bromination reactions were effective by using this protocol. Upon reaction with different nucleophiles, the C?Br bond in the brominated product could be readily transformed to a series of C?C, C?O, C?N, C?S, C?P, and C?I bonds, some of which are difficult to forge with α-halo sp2-B boronate esters. An activation effect of B(MIDA) moiety was found.